Electrocardiography in Chagas' heart disease

Bibliographic Details
Main Author: Garzon, Sérgio A.C.
Publication Date: 1995
Other Authors: Lorga, Adalberto M., Nicolau, José Carlos
Format: Article
Language: eng
Source: São Paulo medical journal (Online)
Download full: https://periodicosapm.emnuvens.com.br/spmj/article/view/1661
Summary: Conventional ECG still plays an important role in the overall knowledge of Chagas' cardiopathy, because of its importance in longitudinal and epidemiological studies, its diagnostic value, and its utility in prognostic evaluation. The authors discuss these aspects, as well as the use of ECG in the acute phase and the significance of a normal ECG in Chagas' disease. Correlations were made between ECG and hemodynamic/angiographic variables among 1010 patients with positive laboratory tests for Chagas' disease: a) in the group with normal ECG there were no significant differences between symptomatic and non-symptomatic patients with regard to ejection fraction and angiographic abnormalities; b) slight abnormalities on the ECG corresponded to an intermediate level of severity of the disease, that is, between normal ECG and ECG with significant abnormalities; c) fibrosis on the ECG was not predictive of akinesia in the related area on the angiography; d) combined ECG abnormalities generally correlated with greater myocardial compromise compared to isolated abnormalities; e) under multiple regression analysis the ECG abnormalities that independently correlated with depressed ejection fraction were: premature ventricular beats, ventricular tachycardia, left bundle branch block, atrial fibrillation, complete AV block, and anterior and inferior fibrosis. Male sex, cardiac insufficiency and cardiomegaly on the thorax radiography were also significantly related.
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spelling Electrocardiography in Chagas' heart diseaseElectrocardiographyChagasic cardiopathyAmerican trypanosomiasisConventional ECG still plays an important role in the overall knowledge of Chagas' cardiopathy, because of its importance in longitudinal and epidemiological studies, its diagnostic value, and its utility in prognostic evaluation. The authors discuss these aspects, as well as the use of ECG in the acute phase and the significance of a normal ECG in Chagas' disease. Correlations were made between ECG and hemodynamic/angiographic variables among 1010 patients with positive laboratory tests for Chagas' disease: a) in the group with normal ECG there were no significant differences between symptomatic and non-symptomatic patients with regard to ejection fraction and angiographic abnormalities; b) slight abnormalities on the ECG corresponded to an intermediate level of severity of the disease, that is, between normal ECG and ECG with significant abnormalities; c) fibrosis on the ECG was not predictive of akinesia in the related area on the angiography; d) combined ECG abnormalities generally correlated with greater myocardial compromise compared to isolated abnormalities; e) under multiple regression analysis the ECG abnormalities that independently correlated with depressed ejection fraction were: premature ventricular beats, ventricular tachycardia, left bundle branch block, atrial fibrillation, complete AV block, and anterior and inferior fibrosis. Male sex, cardiac insufficiency and cardiomegaly on the thorax radiography were also significantly related.O ECG convencional ainda desempenha papel importante no conhecimento da cardiopatia chagásica, pela sua importância nos estudos longitudionais e epidemiológicos, pelo seu valor diagnóstico e utilidade na avaliação prognóstica. Estes aspectos são revistos e discutidos neste artigo, assim como o ECG na fase aguda e o significado do ECG normal na Doença de Chagas. Numa casuística de 1.010 soropositivos foram feitas correlações entre as alterações do ECG e parâmetros hemodinâmicos e cineangiográficos: a) a presença ou não de sintomas nos indivíduos com ECG normal não correspondeu a diferenças nas prevalências de alterações na cineangioventriculografia ou de fração de ejeção de ventrículo esquerdo deprimida; b) um "ECG pouco alterado" corresponde a uma gravidade intermediária entre o ECG normal e o ECG com alterações mais importantes quanto à fração de ejeção e alterações na cineangioventriculografia de ventrículo esquerdo; c) áreas inativadas no ECG não tiveram valor preditivo para detectar assinergias em paredes correspondentes na cineangioventriculografia; d) as alterações combinadas do ECG geralmente correspondem a maior comprometimento miocárdico que as isoladas; e) as alterações eletrocardiográficas que se relacionaram independentemente com a fração de ejeção deprimida em análises de regressão múltipla foram: extrassístoles ventriculares, taquicardia ventricular, bloqueio do ramo esquerdo, fibrilação atrial, bloqueio atrioventricular total e áreas inativadas anterior e inferior. O sexo masculino, a insuficiência cardíaca e a cardiomegalia ao radiografia do tórax também se relacionaram significativamente.São Paulo Medical JournalSão Paulo Medical Journal1995-03-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicosapm.emnuvens.com.br/spmj/article/view/1661São Paulo Medical Journal; Vol. 113 No. 2 (1995); 802-813São Paulo Medical Journal; v. 113 n. 2 (1995); 802-8131806-9460reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APMenghttps://periodicosapm.emnuvens.com.br/spmj/article/view/1661/1556https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessGarzon, Sérgio A.C.Lorga, Adalberto M.Nicolau, José Carlos2023-09-12T10:53:33Zoai:ojs.diagnosticoetratamento.emnuvens.com.br:article/1661Revistahttp://www.scielo.br/spmjPUBhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2023-09-12T10:53:33São Paulo medical journal (Online) - Associação Paulista de Medicinafalse
dc.title.none.fl_str_mv Electrocardiography in Chagas' heart disease
title Electrocardiography in Chagas' heart disease
spellingShingle Electrocardiography in Chagas' heart disease
Garzon, Sérgio A.C.
Electrocardiography
Chagasic cardiopathy
American trypanosomiasis
title_short Electrocardiography in Chagas' heart disease
title_full Electrocardiography in Chagas' heart disease
title_fullStr Electrocardiography in Chagas' heart disease
title_full_unstemmed Electrocardiography in Chagas' heart disease
title_sort Electrocardiography in Chagas' heart disease
author Garzon, Sérgio A.C.
author_facet Garzon, Sérgio A.C.
Lorga, Adalberto M.
Nicolau, José Carlos
author_role author
author2 Lorga, Adalberto M.
Nicolau, José Carlos
author2_role author
author
dc.contributor.author.fl_str_mv Garzon, Sérgio A.C.
Lorga, Adalberto M.
Nicolau, José Carlos
dc.subject.por.fl_str_mv Electrocardiography
Chagasic cardiopathy
American trypanosomiasis
topic Electrocardiography
Chagasic cardiopathy
American trypanosomiasis
description Conventional ECG still plays an important role in the overall knowledge of Chagas' cardiopathy, because of its importance in longitudinal and epidemiological studies, its diagnostic value, and its utility in prognostic evaluation. The authors discuss these aspects, as well as the use of ECG in the acute phase and the significance of a normal ECG in Chagas' disease. Correlations were made between ECG and hemodynamic/angiographic variables among 1010 patients with positive laboratory tests for Chagas' disease: a) in the group with normal ECG there were no significant differences between symptomatic and non-symptomatic patients with regard to ejection fraction and angiographic abnormalities; b) slight abnormalities on the ECG corresponded to an intermediate level of severity of the disease, that is, between normal ECG and ECG with significant abnormalities; c) fibrosis on the ECG was not predictive of akinesia in the related area on the angiography; d) combined ECG abnormalities generally correlated with greater myocardial compromise compared to isolated abnormalities; e) under multiple regression analysis the ECG abnormalities that independently correlated with depressed ejection fraction were: premature ventricular beats, ventricular tachycardia, left bundle branch block, atrial fibrillation, complete AV block, and anterior and inferior fibrosis. Male sex, cardiac insufficiency and cardiomegaly on the thorax radiography were also significantly related.
publishDate 1995
dc.date.none.fl_str_mv 1995-03-03
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicosapm.emnuvens.com.br/spmj/article/view/1661
url https://periodicosapm.emnuvens.com.br/spmj/article/view/1661
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://periodicosapm.emnuvens.com.br/spmj/article/view/1661/1556
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv São Paulo Medical Journal
São Paulo Medical Journal
publisher.none.fl_str_mv São Paulo Medical Journal
São Paulo Medical Journal
dc.source.none.fl_str_mv São Paulo Medical Journal; Vol. 113 No. 2 (1995); 802-813
São Paulo Medical Journal; v. 113 n. 2 (1995); 802-813
1806-9460
reponame:São Paulo medical journal (Online)
instname:Associação Paulista de Medicina
instacron:APM
instname_str Associação Paulista de Medicina
instacron_str APM
institution APM
reponame_str São Paulo medical journal (Online)
collection São Paulo medical journal (Online)
repository.name.fl_str_mv São Paulo medical journal (Online) - Associação Paulista de Medicina
repository.mail.fl_str_mv revistas@apm.org.br
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