Electrocardiography in Chagas' heart disease
Main Author: | |
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Publication Date: | 1995 |
Other Authors: | , |
Format: | Article |
Language: | eng |
Source: | São Paulo medical journal (Online) |
Download full: | https://periodicosapm.emnuvens.com.br/spmj/article/view/1661 |
Summary: | Conventional ECG still plays an important role in the overall knowledge of Chagas' cardiopathy, because of its importance in longitudinal and epidemiological studies, its diagnostic value, and its utility in prognostic evaluation. The authors discuss these aspects, as well as the use of ECG in the acute phase and the significance of a normal ECG in Chagas' disease. Correlations were made between ECG and hemodynamic/angiographic variables among 1010 patients with positive laboratory tests for Chagas' disease: a) in the group with normal ECG there were no significant differences between symptomatic and non-symptomatic patients with regard to ejection fraction and angiographic abnormalities; b) slight abnormalities on the ECG corresponded to an intermediate level of severity of the disease, that is, between normal ECG and ECG with significant abnormalities; c) fibrosis on the ECG was not predictive of akinesia in the related area on the angiography; d) combined ECG abnormalities generally correlated with greater myocardial compromise compared to isolated abnormalities; e) under multiple regression analysis the ECG abnormalities that independently correlated with depressed ejection fraction were: premature ventricular beats, ventricular tachycardia, left bundle branch block, atrial fibrillation, complete AV block, and anterior and inferior fibrosis. Male sex, cardiac insufficiency and cardiomegaly on the thorax radiography were also significantly related. |
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Electrocardiography in Chagas' heart diseaseElectrocardiographyChagasic cardiopathyAmerican trypanosomiasisConventional ECG still plays an important role in the overall knowledge of Chagas' cardiopathy, because of its importance in longitudinal and epidemiological studies, its diagnostic value, and its utility in prognostic evaluation. The authors discuss these aspects, as well as the use of ECG in the acute phase and the significance of a normal ECG in Chagas' disease. Correlations were made between ECG and hemodynamic/angiographic variables among 1010 patients with positive laboratory tests for Chagas' disease: a) in the group with normal ECG there were no significant differences between symptomatic and non-symptomatic patients with regard to ejection fraction and angiographic abnormalities; b) slight abnormalities on the ECG corresponded to an intermediate level of severity of the disease, that is, between normal ECG and ECG with significant abnormalities; c) fibrosis on the ECG was not predictive of akinesia in the related area on the angiography; d) combined ECG abnormalities generally correlated with greater myocardial compromise compared to isolated abnormalities; e) under multiple regression analysis the ECG abnormalities that independently correlated with depressed ejection fraction were: premature ventricular beats, ventricular tachycardia, left bundle branch block, atrial fibrillation, complete AV block, and anterior and inferior fibrosis. Male sex, cardiac insufficiency and cardiomegaly on the thorax radiography were also significantly related.O ECG convencional ainda desempenha papel importante no conhecimento da cardiopatia chagásica, pela sua importância nos estudos longitudionais e epidemiológicos, pelo seu valor diagnóstico e utilidade na avaliação prognóstica. Estes aspectos são revistos e discutidos neste artigo, assim como o ECG na fase aguda e o significado do ECG normal na Doença de Chagas. Numa casuística de 1.010 soropositivos foram feitas correlações entre as alterações do ECG e parâmetros hemodinâmicos e cineangiográficos: a) a presença ou não de sintomas nos indivíduos com ECG normal não correspondeu a diferenças nas prevalências de alterações na cineangioventriculografia ou de fração de ejeção de ventrículo esquerdo deprimida; b) um "ECG pouco alterado" corresponde a uma gravidade intermediária entre o ECG normal e o ECG com alterações mais importantes quanto à fração de ejeção e alterações na cineangioventriculografia de ventrículo esquerdo; c) áreas inativadas no ECG não tiveram valor preditivo para detectar assinergias em paredes correspondentes na cineangioventriculografia; d) as alterações combinadas do ECG geralmente correspondem a maior comprometimento miocárdico que as isoladas; e) as alterações eletrocardiográficas que se relacionaram independentemente com a fração de ejeção deprimida em análises de regressão múltipla foram: extrassístoles ventriculares, taquicardia ventricular, bloqueio do ramo esquerdo, fibrilação atrial, bloqueio atrioventricular total e áreas inativadas anterior e inferior. O sexo masculino, a insuficiência cardíaca e a cardiomegalia ao radiografia do tórax também se relacionaram significativamente.São Paulo Medical JournalSão Paulo Medical Journal1995-03-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicosapm.emnuvens.com.br/spmj/article/view/1661São Paulo Medical Journal; Vol. 113 No. 2 (1995); 802-813São Paulo Medical Journal; v. 113 n. 2 (1995); 802-8131806-9460reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APMenghttps://periodicosapm.emnuvens.com.br/spmj/article/view/1661/1556https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessGarzon, Sérgio A.C.Lorga, Adalberto M.Nicolau, José Carlos2023-09-12T10:53:33Zoai:ojs.diagnosticoetratamento.emnuvens.com.br:article/1661Revistahttp://www.scielo.br/spmjPUBhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2023-09-12T10:53:33São Paulo medical journal (Online) - Associação Paulista de Medicinafalse |
dc.title.none.fl_str_mv |
Electrocardiography in Chagas' heart disease |
title |
Electrocardiography in Chagas' heart disease |
spellingShingle |
Electrocardiography in Chagas' heart disease Garzon, Sérgio A.C. Electrocardiography Chagasic cardiopathy American trypanosomiasis |
title_short |
Electrocardiography in Chagas' heart disease |
title_full |
Electrocardiography in Chagas' heart disease |
title_fullStr |
Electrocardiography in Chagas' heart disease |
title_full_unstemmed |
Electrocardiography in Chagas' heart disease |
title_sort |
Electrocardiography in Chagas' heart disease |
author |
Garzon, Sérgio A.C. |
author_facet |
Garzon, Sérgio A.C. Lorga, Adalberto M. Nicolau, José Carlos |
author_role |
author |
author2 |
Lorga, Adalberto M. Nicolau, José Carlos |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Garzon, Sérgio A.C. Lorga, Adalberto M. Nicolau, José Carlos |
dc.subject.por.fl_str_mv |
Electrocardiography Chagasic cardiopathy American trypanosomiasis |
topic |
Electrocardiography Chagasic cardiopathy American trypanosomiasis |
description |
Conventional ECG still plays an important role in the overall knowledge of Chagas' cardiopathy, because of its importance in longitudinal and epidemiological studies, its diagnostic value, and its utility in prognostic evaluation. The authors discuss these aspects, as well as the use of ECG in the acute phase and the significance of a normal ECG in Chagas' disease. Correlations were made between ECG and hemodynamic/angiographic variables among 1010 patients with positive laboratory tests for Chagas' disease: a) in the group with normal ECG there were no significant differences between symptomatic and non-symptomatic patients with regard to ejection fraction and angiographic abnormalities; b) slight abnormalities on the ECG corresponded to an intermediate level of severity of the disease, that is, between normal ECG and ECG with significant abnormalities; c) fibrosis on the ECG was not predictive of akinesia in the related area on the angiography; d) combined ECG abnormalities generally correlated with greater myocardial compromise compared to isolated abnormalities; e) under multiple regression analysis the ECG abnormalities that independently correlated with depressed ejection fraction were: premature ventricular beats, ventricular tachycardia, left bundle branch block, atrial fibrillation, complete AV block, and anterior and inferior fibrosis. Male sex, cardiac insufficiency and cardiomegaly on the thorax radiography were also significantly related. |
publishDate |
1995 |
dc.date.none.fl_str_mv |
1995-03-03 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicosapm.emnuvens.com.br/spmj/article/view/1661 |
url |
https://periodicosapm.emnuvens.com.br/spmj/article/view/1661 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://periodicosapm.emnuvens.com.br/spmj/article/view/1661/1556 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
São Paulo Medical Journal São Paulo Medical Journal |
publisher.none.fl_str_mv |
São Paulo Medical Journal São Paulo Medical Journal |
dc.source.none.fl_str_mv |
São Paulo Medical Journal; Vol. 113 No. 2 (1995); 802-813 São Paulo Medical Journal; v. 113 n. 2 (1995); 802-813 1806-9460 reponame:São Paulo medical journal (Online) instname:Associação Paulista de Medicina instacron:APM |
instname_str |
Associação Paulista de Medicina |
instacron_str |
APM |
institution |
APM |
reponame_str |
São Paulo medical journal (Online) |
collection |
São Paulo medical journal (Online) |
repository.name.fl_str_mv |
São Paulo medical journal (Online) - Associação Paulista de Medicina |
repository.mail.fl_str_mv |
revistas@apm.org.br |
_version_ |
1825135066587594752 |