Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations

Bibliographic Details
Main Author: Duarte,Fernando Barroso
Publication Date: 2016
Other Authors: Prado,Benedito de Pina Almeida, Vieira,Garles Miller Matias, Costa,Luciano J.
Format: Article
Language: eng
Source: Revista da Associação Médica Brasileira (Online)
Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016001200010
Summary: SUMMARY Selected patients with certain hematological malignancies and solid tumors have the potential to achieve long-term survival with autologous hematopoietic progenitor cell transplant. The collection of these cells in peripheral blood avoids multiple bone marrow aspirations, results in faster engraftment and allows treatment of patients with infection, fibrosis, or bone marrow hypocellularity. However, for the procedure to be successful, it is essential to mobilize a sufficient number of progenitor cells from the bone marrow into the blood circulation. Therefore, a group of Brazilian experts met in order to develop recommendations for mobilization strategies adapted to the reality of the Brazilian national health system, which could help minimize the risk of failure, reduce toxicity and improve the allocation of financial resources.
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spelling Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendationsHematopoietic stem cell mobilizationAutologous transplantationPlerixaforG-CSFSUMMARY Selected patients with certain hematological malignancies and solid tumors have the potential to achieve long-term survival with autologous hematopoietic progenitor cell transplant. The collection of these cells in peripheral blood avoids multiple bone marrow aspirations, results in faster engraftment and allows treatment of patients with infection, fibrosis, or bone marrow hypocellularity. However, for the procedure to be successful, it is essential to mobilize a sufficient number of progenitor cells from the bone marrow into the blood circulation. Therefore, a group of Brazilian experts met in order to develop recommendations for mobilization strategies adapted to the reality of the Brazilian national health system, which could help minimize the risk of failure, reduce toxicity and improve the allocation of financial resources.Associação Médica Brasileira2016-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016001200010Revista da Associação Médica Brasileira v.62 suppl.1 2016reponame:Revista da Associação Médica Brasileira (Online)instname:Associação Médica Brasileira (AMB)instacron:AMB10.1590/1806-9282.62.suppl1.10info:eu-repo/semantics/openAccessDuarte,Fernando BarrosoPrado,Benedito de Pina AlmeidaVieira,Garles Miller MatiasCosta,Luciano J.eng2016-12-01T00:00:00Zoai:scielo:S0104-42302016001200010Revistahttps://ramb.amb.org.br/ultimas-edicoes/#https://old.scielo.br/oai/scielo-oai.php||ramb@amb.org.br1806-92820104-4230opendoar:2016-12-01T00:00Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB)false
dc.title.none.fl_str_mv Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
title Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
spellingShingle Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
Duarte,Fernando Barroso
Hematopoietic stem cell mobilization
Autologous transplantation
Plerixafor
G-CSF
title_short Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
title_full Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
title_fullStr Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
title_full_unstemmed Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
title_sort Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations
author Duarte,Fernando Barroso
author_facet Duarte,Fernando Barroso
Prado,Benedito de Pina Almeida
Vieira,Garles Miller Matias
Costa,Luciano J.
author_role author
author2 Prado,Benedito de Pina Almeida
Vieira,Garles Miller Matias
Costa,Luciano J.
author2_role author
author
author
dc.contributor.author.fl_str_mv Duarte,Fernando Barroso
Prado,Benedito de Pina Almeida
Vieira,Garles Miller Matias
Costa,Luciano J.
dc.subject.por.fl_str_mv Hematopoietic stem cell mobilization
Autologous transplantation
Plerixafor
G-CSF
topic Hematopoietic stem cell mobilization
Autologous transplantation
Plerixafor
G-CSF
description SUMMARY Selected patients with certain hematological malignancies and solid tumors have the potential to achieve long-term survival with autologous hematopoietic progenitor cell transplant. The collection of these cells in peripheral blood avoids multiple bone marrow aspirations, results in faster engraftment and allows treatment of patients with infection, fibrosis, or bone marrow hypocellularity. However, for the procedure to be successful, it is essential to mobilize a sufficient number of progenitor cells from the bone marrow into the blood circulation. Therefore, a group of Brazilian experts met in order to develop recommendations for mobilization strategies adapted to the reality of the Brazilian national health system, which could help minimize the risk of failure, reduce toxicity and improve the allocation of financial resources.
publishDate 2016
dc.date.none.fl_str_mv 2016-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1806-9282.62.suppl1.10
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dc.publisher.none.fl_str_mv Associação Médica Brasileira
publisher.none.fl_str_mv Associação Médica Brasileira
dc.source.none.fl_str_mv Revista da Associação Médica Brasileira v.62 suppl.1 2016
reponame:Revista da Associação Médica Brasileira (Online)
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