Analysis on reoperations and impact on the pancreas transplantation results
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2009 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Brazilian Journal of Transplantation |
| Texto Completo: | https://bjt.emnuvens.com.br/revista/article/view/249 |
Resumo: | Many factors which include advancements in the surgery techniques and immunosuppression have been brought significant improvement on the results of the graft and patient survival submitted to pancreatic transplants. However, a third part of these patients is submitted to reoperations (ReOps). Purposes: To assess the distribution of ReOps among the PT categories in the post-operatory period (premature or late) and to analyze the impact of these operations on the patient and graft survival. Methods: Unicentric, retrospective study carried out through the data collection from charts of 182 patients submitted to PT from January of 2000 until December of 2007. Results: 88 reoperations were performed in 73 patients, being 43 premature operations, and 41 late operations. PTRS group presented higher incidence of premature ReOps related to other groups. The group submitted to premature ReOp presented lower survival rate (87.2%) when compared to the non-operated group, and a similar survival rate (97.5%) when compared to the group submitted to late ReOp. Related to the pancreatic grafting survival after one year, it was verified that the premature ReOp group had a lower survival rate compared to the late ReOp group, both presenting significantly worse results then the group with no ReOp. Conclusion: Post-PT ReOps has a direct relationship towards a successful procedure. When performed in the first 3 months after PT, they determined a negative impact on the survival of patient and graft. |
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Analysis on reoperations and impact on the pancreas transplantation resultsANÁLISE DAS REOPERAÇÕES E DE SEU IMPACTO NOS RESULTADOS DOS TRANSPLANTES DE PÂNCREASDiabetes MellitusTipo 1TransplanteTransplante de PâncreasRejeiçãoImunosupressãoDiabetes Mellitus Type 1TransplantationPancreas TransplantationRejectionImunosupressionMany factors which include advancements in the surgery techniques and immunosuppression have been brought significant improvement on the results of the graft and patient survival submitted to pancreatic transplants. However, a third part of these patients is submitted to reoperations (ReOps). Purposes: To assess the distribution of ReOps among the PT categories in the post-operatory period (premature or late) and to analyze the impact of these operations on the patient and graft survival. Methods: Unicentric, retrospective study carried out through the data collection from charts of 182 patients submitted to PT from January of 2000 until December of 2007. Results: 88 reoperations were performed in 73 patients, being 43 premature operations, and 41 late operations. PTRS group presented higher incidence of premature ReOps related to other groups. The group submitted to premature ReOp presented lower survival rate (87.2%) when compared to the non-operated group, and a similar survival rate (97.5%) when compared to the group submitted to late ReOp. Related to the pancreatic grafting survival after one year, it was verified that the premature ReOp group had a lower survival rate compared to the late ReOp group, both presenting significantly worse results then the group with no ReOp. Conclusion: Post-PT ReOps has a direct relationship towards a successful procedure. When performed in the first 3 months after PT, they determined a negative impact on the survival of patient and graft.Introdução: Diversos fatores, incluindo avanços da técnica cirúrgica e a imunossupressão, entre outros, têm trazido significativa melhora nos resultados da sobrevivência do enxerto e dos pacientes submetidos a Transplante de Pâncreas (TP). No entanto, um terço desses pacientes é submetido a reoperações (ReOps). Objetivos: Avaliar a distribuição das ReOps nas categorias de TP, no período pós-operatório (precoce ou tardio) e analisar o impacto das mesmas na sobrevida de pacientes e enxertos. Métodos: Estudo unicêntrico, retrospectivo realizado através da coleta de dados do prontuário de 182 pacientes submetidos ao TP de janeiro de 2000 a dezembro de 2007. Resultados: 88 reoperações foram realizadas em 73 pacientes, sendo 47 precoces e 41 tardias. O grupo TPRS apresentou maior incidência de ReOp precoce em relação aos demais grupos. O grupo submetido à ReOp precoce apresentou menor sobrevida (87,2%) quando comparado ao grupo não reoperado e semelhante ao grupo submetido à ReOp tardia (97,5%). Em relação à sobrevida em um ano do enxerto pancreático, verificamos que o grupo ReOp precoce foi inferior quando comparado ao grupo ReOp tardia e ambos apresentaram resultados significativamente piores em relação ao grupo sem ReOp. Conclusão: ReOps após o TP estão diretamente relacionadas ao sucesso do procedimento. Quando realizadas nos três primeiros meses após TP, determinaram impacto negativo na sobrevida em um ano de paciente e enxerto.Associação Brasileira de Transplante de Órgãos (ABTO)2009-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://bjt.emnuvens.com.br/revista/article/view/24910.53855/bjt.v12i1.249Brazilian Journal of Transplantation; Vol. 12 No. 1 (2009); 1010-1044Brazilian Journal of Transplantation; v. 12 n. 1 (2009); 1010-10442764-1589reponame:Brazilian Journal of Transplantationinstname:Associação Brasileira de Transplante de Órgãos (ABTO)instacron:ABTOporhttps://bjt.emnuvens.com.br/revista/article/view/249/233Copyright (c) 2021 Brazilian Journal of Transplantationinfo:eu-repo/semantics/openAccessGenzini, TercioCrescentini, FabioCarneiro, ArieRangel, Erika BevilaquaAntunes, IrinaSakuma, HebertScomparin, Patrick SalomãoFerreira, Felipe YamautiMiranda, Marcelo Perosa de2021-09-28T14:24:38Zoai:ojs3.emnuvens.com.br:article/249Revistahttps://bjt.emnuvens.com.br/revistaONGhttps://bjt.emnuvens.com.br/revista/oaibjt@abto.org.brhttps://doi.org/10.53855/2764-15892764-1589opendoar:2021-09-28T14:24:38Brazilian Journal of Transplantation - Associação Brasileira de Transplante de Órgãos (ABTO)false |
| dc.title.none.fl_str_mv |
Analysis on reoperations and impact on the pancreas transplantation results ANÁLISE DAS REOPERAÇÕES E DE SEU IMPACTO NOS RESULTADOS DOS TRANSPLANTES DE PÂNCREAS |
| title |
Analysis on reoperations and impact on the pancreas transplantation results |
| spellingShingle |
Analysis on reoperations and impact on the pancreas transplantation results Genzini, Tercio Diabetes MellitusTipo 1 Transplante Transplante de Pâncreas Rejeição Imunosupressão Diabetes Mellitus Type 1 Transplantation Pancreas Transplantation Rejection Imunosupression |
| title_short |
Analysis on reoperations and impact on the pancreas transplantation results |
| title_full |
Analysis on reoperations and impact on the pancreas transplantation results |
| title_fullStr |
Analysis on reoperations and impact on the pancreas transplantation results |
| title_full_unstemmed |
Analysis on reoperations and impact on the pancreas transplantation results |
| title_sort |
Analysis on reoperations and impact on the pancreas transplantation results |
| author |
Genzini, Tercio |
| author_facet |
Genzini, Tercio Crescentini, Fabio Carneiro, Arie Rangel, Erika Bevilaqua Antunes, Irina Sakuma, Hebert Scomparin, Patrick Salomão Ferreira, Felipe Yamauti Miranda, Marcelo Perosa de |
| author_role |
author |
| author2 |
Crescentini, Fabio Carneiro, Arie Rangel, Erika Bevilaqua Antunes, Irina Sakuma, Hebert Scomparin, Patrick Salomão Ferreira, Felipe Yamauti Miranda, Marcelo Perosa de |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Genzini, Tercio Crescentini, Fabio Carneiro, Arie Rangel, Erika Bevilaqua Antunes, Irina Sakuma, Hebert Scomparin, Patrick Salomão Ferreira, Felipe Yamauti Miranda, Marcelo Perosa de |
| dc.subject.por.fl_str_mv |
Diabetes MellitusTipo 1 Transplante Transplante de Pâncreas Rejeição Imunosupressão Diabetes Mellitus Type 1 Transplantation Pancreas Transplantation Rejection Imunosupression |
| topic |
Diabetes MellitusTipo 1 Transplante Transplante de Pâncreas Rejeição Imunosupressão Diabetes Mellitus Type 1 Transplantation Pancreas Transplantation Rejection Imunosupression |
| description |
Many factors which include advancements in the surgery techniques and immunosuppression have been brought significant improvement on the results of the graft and patient survival submitted to pancreatic transplants. However, a third part of these patients is submitted to reoperations (ReOps). Purposes: To assess the distribution of ReOps among the PT categories in the post-operatory period (premature or late) and to analyze the impact of these operations on the patient and graft survival. Methods: Unicentric, retrospective study carried out through the data collection from charts of 182 patients submitted to PT from January of 2000 until December of 2007. Results: 88 reoperations were performed in 73 patients, being 43 premature operations, and 41 late operations. PTRS group presented higher incidence of premature ReOps related to other groups. The group submitted to premature ReOp presented lower survival rate (87.2%) when compared to the non-operated group, and a similar survival rate (97.5%) when compared to the group submitted to late ReOp. Related to the pancreatic grafting survival after one year, it was verified that the premature ReOp group had a lower survival rate compared to the late ReOp group, both presenting significantly worse results then the group with no ReOp. Conclusion: Post-PT ReOps has a direct relationship towards a successful procedure. When performed in the first 3 months after PT, they determined a negative impact on the survival of patient and graft. |
| publishDate |
2009 |
| dc.date.none.fl_str_mv |
2009-01-01 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://bjt.emnuvens.com.br/revista/article/view/249 10.53855/bjt.v12i1.249 |
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https://bjt.emnuvens.com.br/revista/article/view/249 |
| identifier_str_mv |
10.53855/bjt.v12i1.249 |
| dc.language.iso.fl_str_mv |
por |
| language |
por |
| dc.relation.none.fl_str_mv |
https://bjt.emnuvens.com.br/revista/article/view/249/233 |
| dc.rights.driver.fl_str_mv |
Copyright (c) 2021 Brazilian Journal of Transplantation info:eu-repo/semantics/openAccess |
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Copyright (c) 2021 Brazilian Journal of Transplantation |
| eu_rights_str_mv |
openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Associação Brasileira de Transplante de Órgãos (ABTO) |
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Associação Brasileira de Transplante de Órgãos (ABTO) |
| dc.source.none.fl_str_mv |
Brazilian Journal of Transplantation; Vol. 12 No. 1 (2009); 1010-1044 Brazilian Journal of Transplantation; v. 12 n. 1 (2009); 1010-1044 2764-1589 reponame:Brazilian Journal of Transplantation instname:Associação Brasileira de Transplante de Órgãos (ABTO) instacron:ABTO |
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Associação Brasileira de Transplante de Órgãos (ABTO) |
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ABTO |
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ABTO |
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Brazilian Journal of Transplantation |
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Brazilian Journal of Transplantation |
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Brazilian Journal of Transplantation - Associação Brasileira de Transplante de Órgãos (ABTO) |
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bjt@abto.org.br |
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1836111233945698304 |