In Vitro studies of bioactive glass/polyhydroxybutyrate composites

• Main Author: Paiva,André Oliveira
• Publication Date: 2006
• Other Authors: Duarte,Maria Gabriela, Fernandes,Maria Helena Vaz, Gil,Maria Helena, Costa,Necésio Gomes
• Format: Article
• Language: eng
• Source: Materials research (São Carlos. Online)
• Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392006000400013
• topic: bioactive glasses; polyhydroxybutyrate; composites and bioactivity

Bioactive materials can help bone reparation and regeneration by offering support to bone growth. In vitro studies of bioactive glass/polyhydroxybutyrate composites were carried out to evaluate the influence of the composition on the bioactivity through the presence of calcium phosphate (Ca-P) on the layer formed when the substrates were immerse in simulated body fluid (SBF). The in vitro tests were carried out by soaking the composites bioactive glass/polyhydroxybutyrate 30/70 and 40/60 in SBF. The surface of the composites was analyzed by Scanning Electron Microscopy (SEM) with Energy Dispersive Spectroscopy (EDS) and also via x ray Diffraction (XRD). The solutions were analyzed by Inductively Couple Plasma (ICP). SEM images show a formation of a Ca-P rich layer on surface of composites. XRD results characterized the layer as calcium hydrogen phosphate. Ca/P ratios found via EDS results show a value close to 1.67. According to ICP results, the Ca e P ions are from SBF.