Heritability in social anxiety disorder and its impact on executive functioning, facial expression recognition, and symptomatic profile

• Ano de defesa: 2018
• Autor(a) principal: Silva, André Luiz Moreno da
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: eng
• Instituição de defesa: Biblioteca Digitais de Teses e Dissertações da USP
• Palavras-chave em Português: Executive functioning; Facial emotion recognition; Funções executivas; Herdabilidade; Heritability; Negative repetitive thoughts; Pensamentos negativos repetitivos; Reconhecimento de expressão facial; Social anxiety disorder; Transtorno de ansiedade social
• Link de acesso: http://www.teses.usp.br/teses/disponiveis/17/17148/tde-27052019-134433/

Social Anxiety Disorder (SAD) is a mental disorder characterized by fear and anxiety in social situations that lead to functioning impairment and suffering. Although a very frequent disorder among the population, some aspects of development and maintenance of SAD are still unclear. This doctoral dissertation is divided into five articles, that aimed to explore some of these gaps in previous studies. The first one describes the Cross-cultural Adaptation and Psychometric Properties of the Brazilian Version of the Thought Control Questionnaire, a measure of Negative Repetitive Thoughts frequently reported as a variable related to SAD. The second one is a systematic review of different methods and perspectives in the estimative of heritability of SAD. The third one describes a twin study that aimed to estimate the heritability of SAD in Brazil. The fourth one describes an experimental cross-over study designed to evaluate cognitive deficits in executive functioning in an anxiety-induced condition and to estimate the heritability of these deficits. Lastly, the fifth describes an experimental cross-over study aimed to evaluate the accuracy and intensity of facial emotion recognition in an anxiety-induced condition and to estimate the impact of heritability in the recognition. Together, these five articles provide valuable insights that help understand the development and maintenance of SAD.