Biomaterial composto de hidroxiapatita e de fibroína oriunda de resíduo da indústria de seda

• Ano de defesa: 2018
• Autor(a) principal: Fontes, Elder Bruno
• Orientador(a): Kinoshita, Angela Mitie Otta
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade do Sagrado Coração
• Programa de Pós-Graduação: Ciência e Tecnologia Ambiental
• Departamento: Ciências Exatas e Sociais Aplicadas
• País: Brasil
• Palavras-chave em Português: Resíduo industrial; Biomateriais; Cerâmica; Valorização de resíduos; Controle de poluição
• Palavras-chave em Inglês: Industrial waste; Biomaterials; Ceramics; Waste recovery; Pollution Control
• Área do conhecimento CNPq: CIENCIAS EXATAS E DA TERRA
• Link de acesso: http://tede2.usc.br:8080/jspui/handle/tede/413

The search for sustainable means has been developed studies and research of use of waste in several areas. The obtaining of biomaterials from these is one of the forms of exploitation that brings as a benefit its valorization. From this context, this work presents the use of silk industry waste as a raw material to obtain biomaterials. Silk is composed of two proteins: the fibroin which is the silk filament, and the sericin that holds the strands together. Silk fibroin exhibits properties of biocompatibility, mechanical strength, high thermal stability, microbial resistance and the fact that it can be processed in various forms such as powders, films, membranes and hydrogels. Such characteristics justify its application in biomaterials. Fibroin was obtained by degumming the silk residue, complete dissolution was performed with ternary CaCl2:CH3CH2OH:H2O (1: 2: 8 molar) rate. The introduction of hydroxyapatite occurred with the addition of bibasic disodium phosphate (Na2HPO4) in the dissolved fibroin solution. Precipitation of the compounds gave rise to the fibroin/hydroxyapatite composite. The X-ray diffractogram showed that the mineral part consists of hydroxyapatite. The Infrared Spectrum confirms the formation of the composite, demonstrating functional amide groups from fibroin and other functional groups such as hydroxyapatite phosphates. The thermal analyzes of TG/DTG and DTA confirm the presence of organic and inorganic material and present the thermal stability of the biomaterial. Thus, the possibility of using fibroin extracted from silk industry waste as a component of a potential new biomaterial was demonstrated.