Análise da saliva de pacientes com ardência bucal por espectroscopia de Fourier Transform Infrared (FT-IR)

• Ano de defesa: 2013
• Autor(a) principal: Carvalho, Lais Morandini [UNESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Estadual Paulista (Unesp)
• Palavras-chave em Português: Análise espectral; Saliva; Boca - Doenças - Diagnóstico; Biopsia
• Link de acesso: http://hdl.handle.net/11449/108836

The optical biopsy techniques consist in the analysis of tissues through its physical properties. Among these techniques, there is a Fourier Transform Infrared (FT-IR) spectroscopy, which has been used to identify patterns of molecular changes through vibrational modes. The aim of this study was to evaluate by FT-IR spectroscopy saliva samples from 14 patients complaining of burning mouth aiming to study global biochemical changes and compare the saliva of 14 patients without any complaint, matched for age and sex. To obtain results, the spectra acquired and stored by the control software of the spectrometer Fourier Transform Infrared (FT-IR) were converted to ASCII format for further processing and analysis be conducted in Minitab 16. The results revealed by the analysis performed by the graphics program Origin and Qytplot that there were differences in the intensities of the bands related to proteins and lipids, who presented with lower spectral intensity to the saliva of patients with burning complain. Therefore, it was concluded that the technique was effective for characterizing the presence of changes in the saliva of patients with burning compared saliva from normal patients