Objective assessment of motor symptoms of Parkinson's disease through non-contact sensors

• Ano de defesa: 2020
• Autor(a) principal: Oliveira, Fábio Henrique Monteiro
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: eng
• Instituição de defesa: Universidade Federal de Uberlândia; Brasil; Programa de Pós-graduação em Engenharia Elétrica
• Palavras-chave em Português: Parkinson's disease; Non-contact capacitive sensor; Inertial sensor; Hand motor task; CNPQ::ENGENHARIAS::ENGENHARIA BIOMEDICA; CNPQ::CIENCIAS EXATAS E DA TERRA::CIENCIA DA COMPUTACAO; CNPQ::ENGENHARIAS::ENGENHARIA ELETRICA
• Link de acesso: https://repositorio.ufu.br/handle/123456789/29174; http://doi.org/10.14393/ufu.te.2020.393

The diagnosis and evaluation of the severity of Parkinson's disease (PD) is a task that has been performed through clinical evaluation and use of subjective scales. Over the years several studies have reported results and technologies with the purpose of making the characterization of PD more objective. In this perspective, we have identified the possibility of using non-contact capacitive sensors to record the motor activity of the hand and wrist. Another identified challenge is related to the quantification of the severity of motor symptoms of PD. In this study, we present the use of an innovative tool, t-Distributed Stochastic Neighbor Embedding (t-SNE), for the reduction and visualization of information. The use of this tool allowed the visualization of data in a two-dimensional space and an improvement of the performance of classifiers responsible for estimating the severity of the disease. In order to evaluate the use of capacitive sensors and signal processing tools, data from neurologically healthy individuals and people with PD were collected. In the end, our contributions are the following: (i) development and evaluation of a technology for recording motor signals of hand and wrist activities, based on capacitive contactless sensors; (ii) comparative evaluation among several tools for signal processing, in order to objectively evaluate the motor symptoms of PD.