Intervenções baseadas em mindfulness para dor neuropática periférica diabética: uma revisão sistemática e meta-análise de ensaios clínicos randomizados

• Ano de defesa: 2023
• Autor(a) principal: Ferreira, Gabriel Ferraz [UNIFESP]
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo
• Palavras-chave em Português: Meditação; Atenção plena; Neuropatias diabéticas; Dor crônica; Diabetes mellitus
• Link de acesso: https://repositorio.unifesp.br/handle/11600/70677

Objective: The objective of this study was to conduct a systematic review with patients diagnosed with diabetic peripheral neuropathy, investigating the effects of mindfulness therapy on pain scores and quality of life, comparing them with control groups. Methods: The studies identified through a systematic review of articles from six electronic databases until April 8, 2023. Relevant randomized controlled trials were selected and evaluated for risk of bias, and data collection was conducted. The results of the combined analysis were summarized based on clinical pain criteria. We utilized the R software to perform both qualitative and quantitative analyses. Results: Seven RCTs of patients with diabetic neuropathic pain treated with mindfulness were included for qualitative assessment. We included six studies in the meta-analysis that investigated the difference in pain scales between the meditation group and the control group. Using the standardized mean difference technique, the random-effects model demonstrated that meditation had a significant effect on pain reduction, with a standardized mean difference of -1.99 (95% confidence interval between -2.29 to -1.68), and improvement in quality of life scores of 4.54 (95% confidence interval between 4.06 to 5.02). In general, the risk of bias was acceptable and low. Conclusion: Mindfulness therapy was effective in reducing pain and improving the quality of life in patients with diabetic peripheral neuropathy. Studies with long-term follow-up should be conducted to confirm these findings.