Intervenções baseadas em mindfulness para dor neuropática periférica diabética: uma revisão sistemática e meta-análise de ensaios clínicos randomizados

Detalhes bibliográficos
Ano de defesa: 2023
Autor(a) principal: Ferreira, Gabriel Ferraz [UNIFESP]
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Tese
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de São Paulo
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: https://repositorio.unifesp.br/handle/11600/70677
Resumo: Objective: The objective of this study was to conduct a systematic review with patients diagnosed with diabetic peripheral neuropathy, investigating the effects of mindfulness therapy on pain scores and quality of life, comparing them with control groups. Methods: The studies identified through a systematic review of articles from six electronic databases until April 8, 2023. Relevant randomized controlled trials were selected and evaluated for risk of bias, and data collection was conducted. The results of the combined analysis were summarized based on clinical pain criteria. We utilized the R software to perform both qualitative and quantitative analyses. Results: Seven RCTs of patients with diabetic neuropathic pain treated with mindfulness were included for qualitative assessment. We included six studies in the meta-analysis that investigated the difference in pain scales between the meditation group and the control group. Using the standardized mean difference technique, the random-effects model demonstrated that meditation had a significant effect on pain reduction, with a standardized mean difference of -1.99 (95% confidence interval between -2.29 to -1.68), and improvement in quality of life scores of 4.54 (95% confidence interval between 4.06 to 5.02). In general, the risk of bias was acceptable and low. Conclusion: Mindfulness therapy was effective in reducing pain and improving the quality of life in patients with diabetic peripheral neuropathy. Studies with long-term follow-up should be conducted to confirm these findings.