Análise das diferenças regionais e tendências temporais das infecções pelos virús HAV, HBV e HCV baseada em sistemas de informação em saúde

• Ano de defesa: 2021
• Autor(a) principal: Grandi, Giuliano [UNIFESP]
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Hepatites Virais Humanas; Epidemiologia; Sistemas De Informação Em Saúde
• Link de acesso: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=9970670; https://repositorio.unifesp.br/handle/11600/68191

Introduction: Viral Hepatitis constitute a worldwide public health concern. Different institutions points to the increase of burden associated with these infections, specially chronic infections. Therefore, the development of health information systems is part of the efforts to control these infections until 2030, as proposed by WHO (World Health Organization). Methods: Analysis of hepatitis A, B and C reported cases from 2007 to 2018, searching for different patterns of population distribution of cases in Brazil and its regions, in addition to temporal trends of reported cases. Results: Hepatitis A: The notification decreased from 2007 to 2018 with AAPC of - 17,5% (95% CI, -22,3% to -12,4%). However, in 2016, 2017 and 2018 an increase in male cases between 20 and 39 years occur in the Southeast region. In addition, reported cases of North, Northeast and Central-West regions are 10 years younger in comparison to the cases of South and Southeast regions. Hepatitis B: The notification of acute cases decreased from 2007 to 2018, with AAPC of -5,3% (95% CI, -9,9% to -0,4%), while the notification of chronic and resolved cases remained stable. In chronic cases above 40 years, the notification of chronic cases increased. Regional analysis shows that in North, Northeast and Central-West regions notification of cases occurs earlier in life, especially female cases. Hepatitis C: The notification of Hepatitis C cases increased from 2007 to 2018, with AAPC of 3,8% (95% CI, 0,9% to 5,6%), while Viremic cases remained stable. In North, Northeast and Central-West regions, cases notification of cases occurs about 6 years earlier than South and Southeast regions. Conclusion: The analysis of SINAN reported cases can identify changes in population dynamics of viral hepatitis cases and regional differences that helps with strategic planning of control measures.