Análise crítica dos métodos de biópsia cerebral canina

• Ano de defesa: 2017
• Autor(a) principal: Abreu, Felipe Andrei Suarez de [UNIFESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Image; Veterinary Guided Biopsy; Biopsy; Methods; Neuronavigation; Veterinary; Biópsia Guiada Por Imagem; Veterinária; Biópsia; Métodos; Neuronavegação
• Link de acesso: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=5069667; http://repositorio.unifesp.br/handle/11600/50323

Introduction: The paradigm of dogs as companion animals changed a lot in the last decades. Many people consider pets as important members of the family, spending time and worrying about healthcare for them. As consequence, animal life expectancy has risen and new diagnostic technologies such as computed tomography and magnetic resonance imaging have been incorporated as veterinary tools, allowing more age related problems to be diagnosed, like cerebral neoplasms. However, imaging is often not enough. The golden pattern for a definitive diagnosis is the histopathology exam. Materials and Methods: In order to find out which brain biopsy technique is the most applicable in a clinical setting on a big Brazilian urban center, with access to computed tomography and magnetic resonance imaging, published series regarding brain biopsy in dogs were reviewed. Of the 165 publications, 23 publications treated this subject as its major topic and were analyzed for four inclusion criteria: use of live animals, thorough description of the method, needle placement error and adverse effects following the procedure Results: 23 articles met totally or partially the inclusion criteria. Only one met all four criteria. The other 22 publications were used to make comparisons about three biopsy techniques: freehand, stereotactic biopsy and neuronavigation Discussion: Freehand biopsy has the lowest accuracy rate and the highest biopsy related morbidity. Stereotactic biopsy is the most complicated technique: there are very few commercially available veterinary systems and all of them need adaptations in order to accommodate different dog sizes. Its accuracy, morbidity and mortality rates ate very variable, probably due to the needed modifications, rending comparison impossible. Neuronavegation have more homogenous results, but it’s still a very new system and more studies are needed. So far, there are only four published papers, each with a different goal. We conclude that, among the analyzed techniques, neuronavigation is the most promising.