Biometria ultrassônica, crescimento ocular e erros refracionais em recém-nascidos pré-termos sem e com retinopatia da prematuridade (ROP) nos estágios 1 e 2

• Ano de defesa: 2020
• Autor(a) principal: Cauduro, Ricardo Salles [UNIFESP]
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Biometric Ocular; Premature Infants; Transpalpebral; Camara Anterior; Anatomia; Histologia; Biometria; Peso Ao Nascimento; Olho
• Link de acesso: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=10041116; https://hdl.handle.net/11600/64863

Purpose: Evaluate biometric ocular parameters, refractive errors and eye growth in a series of premature infants (birth weight under 1,500 g or gestational age less than 32 weeks) with and without retinopathy of prematurity (ROP). Methods: Prospective study in preterm population performed in the pediatric intensive care unit of Hospital São Paulo, Department of Pediatrics, UNIFESP, during the years 2015-2017. Follow-up was fortnightly considering the following intervals of gestational age in weeks: 26-27; 28-29; 30-31; 32-33; 34-35; 36-37; 38-39 and 40-41. Biometric Ocular parameters were obtained using transpalpebral (B-scan ultrasound, 7.5-15 MHz linear transducer, Mylab, Esaote) and included: Anterior chamber depth, lens thickness, vitreous chamber depth and axial length. Ophthalmological exam included refraction (retinoscopy, calculated spherical equivalent) and indirect ophthalmoscopy (28 D lens), screening for ROP. Pediatric parameters included: gestacional age corrected in weeks, weight in grams, head circumference, weight, birth length and Apgar score. Results: 60 eyes of premature newborn were included and analyzed the right eye of 42 premature babies (20 male, 22 female). Through repeated analysis of variance (ANOVA), a statistically significant effect was observed over time, for the studied ocular parameters, and with regard to retinopathy of prematurity, it did not differ significantly from any of the measures evaluated from the rest of the group.The biometric parameter showed a positive correlation relationship with gestacional age, however, the refractive spherical equivalent was observed in an opposite behavior. The lens thickness and refractive spherical equivalent did not show significant correlation with gestational age, only the spherical equivalent showed significant correlation with the z-weight score for gestational age. Conclusions: In this study, it was possible to document the pattern of ocular growth in preterm infants with the progression of gestational age, without differentiation between the groups of preterm infants (with and without retinopathy of prematurity) by validating mode B ultrasound with the eyelid contact technique.