Desenvolvimento farmacotécnico e validação analítica de comprimidos revestidos a partir do extrato padronizado de Actaea racemosa L.

• Ano de defesa: 2017
• Autor(a) principal: Bagatela, Bianca Souza [UNIFESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo
• Palavras-chave em Português: Ranunculaceae; Actaea racemosa L.; 23-epi-26-desoxiactein; Black cohosh; Herbal medicine; 23-epi-26-desoxiacteína; Cimicífuga; Medicamento fitoterápico
• Link de acesso: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=5001739; http://repositorio.unifesp.br/handle/11600/50269

The project aims to develop an herbal medicine from the dry extract, standardized in 23-epi-26-desoxiactein, from the roots of the plant species Actaea racemosa L. (Ranunculaceae), popularly known as "black cohosh". The tablets were developed from the dry extract of A. racemosa L. and produced by direct compression. Subsequently, they were coated with the appropriate dispersion. Accelerated and longterm stability studies have been performed to define the period of use and validity. Coated tablets, obtained from the dried extract of A. racemosa L., were standardized in 23-epi-26-desoxiactein, and the analytical methodology was validated.