Vulnerabilidade e Resiliência ao Estresse: Aspectos ontogenéticos das consequências comportamentais, neuroendócrinas e neuroquímicas

• Ano de defesa: 2013
• Autor(a) principal: Suchecki, Deborah [UNIFESP]
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Hypothalamic-pituitary-adrenal axis; Corticosterone; Maternal deprivation; REM sleep deprivation; Emotional behaviour; Animal models
• Link de acesso: https://repositorio.unifesp.br/handle/11600/58402

This Full Professorship thesis portrays a current and frequently present matter in human daily life, Stress. By means of a broad literature overview, I intend to present the biological foundation of the hormonal and behavioural responses to stressful stimuli throughout life span, with an emphasis in my work. The complete, yet unpublished studies are presented and discussed in the present document. The findings show that outcomes of stressful events depend on the stimulus features and on individual characteristics. Therefore, recruitment of the response systems has the purpose of giving support to necessary and appropriate behaviours for a given situation. However, to be perceived as a stressor, the stimulus must be uncontrollable and unpredictable. As for the individual, coping strategies are of utmost importance and may determine, together with one’s previous history, the success or failure to deal with adverse situations, especially when they are prolonged.