Avaliação de funções executivas, estresse e resiliência em crianças e adolescentes tratados para leucemia linfóide aguda

• Ano de defesa: 2019
• Autor(a) principal: Godoy, Priscilla Brandi Gomes [UNIFESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Executive function; Stress, psychological; Acute lymphoblastic leukemia; Resilience, psychological; Child development; Função executiva; Estresse psicológico; Resiliência psicológica; Leucemia linfóide; Desenvolvimento infantil
• Link de acesso: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=7674168; https://repositorio.unifesp.br/handle/11600/58740

Objective: To investigate the impact of acute lymphoblastic leukemia treatment and parents' emotional characteristics on executive functions, resilience, stress, depression and anxiety in children and adolescents, as well as to verify the strength of the correlations between executive functions, stress and personality traits of resilience. Methods: Thirty-two survivors of acute lymphoblastic leukemia (ALL group), 28 healthy controls (CTL group 1) and three survivors’ siblings (CTL 2 group), all aged between 7 and 17 years, of both sexes, participated in the study. Executive functions were assessed by neuropsychological tests of mental flexibility, inhibitory control, working memory and attention, as well as ecological questionnaires for parents. Stress symptoms and resilience were assessed by self-reported questionnaires for children and symptoms of depression and anxiety, by parent-report behavioral problems scale. The primary caregiver or one parent also answered to self-report questionnaires of depression and anxiety. Results: There was no difference between the CTL 1 and ALL groups regarding the neuropsychological, emotional and resilience assessment. Higher mental flexibility ability were reported by the ALL group parents in BRIEF when compared to CTL1 group. Parents’ depression and anxiety did not influence children’s emotions and resilience in the whole sample, but the parents’ trait anxiety influenced their assessment about their children’s executive functions and behavioral problems in both groups. In the LLA group, positive correlations were observed between executive functions and resilience, and negative correlations were observed between executive functions and stress, which suggests an interaction between these variables to promote survivor’s cognitive and emotional adaptation. Descriptive analysis were made with the CTL 2 group results. Conclusion: acute lymphoblastic leukemia treatment had no impact on the executive functions, resilience, stress symptoms, depression and anxiety of the participants and the correlations found between these variables suggest that these could be protection factors. Parents' emotional aspects influenced their answers about children’s executive functions and behavioral problems. We suggest that parent-report scales for assessment of children’s executive functions and emotions be associated to assessment of parents’ emotional characteristic.