Estudo de parâmetros reacionais em moinho de bolas na síntese de aril(heteroaril)-1h-pirazóis

• Ano de defesa: 2012
• Autor(a) principal: Paveglio, Guilherme Caneppele
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Santa Maria; BR; Química; UFSM; Programa de Pós-Graduação em Química
• Palavras-chave em Português: Enaminonas; Moinho de bolas; Parâmetros; Misturas eutéticas; Calorimetria diferencial de varredura; β-enaminones; Ball mill; Parameters; Eutectic mixtures; Differential scanning calorimetry; CNPQ::CIENCIAS EXATAS E DA TERRA::QUIMICA
• Link de acesso: http://repositorio.ufsm.br/handle/1/10532

This paper describes a study of reaction parameters in a ball mill in the synthesis of 1H-pyrazole acid catalyzed. The studied parameters were: amount of reactants, frequency, reaction time, amount of catalyst, number of milling balls, different catalysts, diameter and material of the milling balls. Another study was conducted to study the mechanism of solid-solid reaction involved in the cyclocondensation between enaminones and hydrazine hydrochloride acid catalyzed. These mixtures were studied by thermal analysis (TGA and DSC), where eight enaminones were evaluated and four eutectic mixtures were identified.