Efeitos do exercício físico resistido sobre a função vascular e pressão arterial em ratos : uma revisão sistemática e meta-análise

• Ano de defesa: 2015
• Autor(a) principal: Silva, Tharciano Luiz Teixeira Braga da
• Orientador(a): Santos, Márcio Roberto Viana dos
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Sergipe
• Programa de Pós-Graduação: Pós-Graduação em Ciências da Saúde
• País: BR
• Palavras-chave em Português: Meta-análise; Exercício resistido; Pressão arterial; Função vascular
• Palavras-chave em Inglês: Meta-analysis; Resistance exercise; Arterial pressure
• Área do conhecimento CNPq: CNPQ::CIENCIAS DA SAUDE
• Link de acesso: https://ri.ufs.br/handle/riufs/3579

Meta-analyses with preclinical studies are relatively new and promote guidelines for clinical studies. The literature has showed that the effects of resistance exercise on the cardiovascular system in experimental models are still controversy. The aim of this metaanalysis was to evaluate the effects of resistance exercise on vascular function and blood pressure in rats. Different databases were searched for studies evaluating the effects of resistance exercise on vascular sensitivity, maximal response and blood pressure in rats up to September 30, 2014. Post intervention between-group effect sizes were pooled with the generic inverse variance method using random-effect model and expressed as standardized mean difference, Hedges g, with 95% confidence intervals (95% CI). Thirteen eligible studies were included. Our meta-analysis showed that resistance exercise in rats does not alter the vascular sensitivity, but promotes increased vascular relaxation (p<0.01). In addition, we observed a reduction in blood pressure in the exercised animals (p<0.01). Subgroup analysis showed that squat exercise (p<0.01), with low volumes of resistance exercise (p<0.05) and with moderate/high intensity (p<0.001) reduces the blood pressure. The results of this meta-analysis suggests that resistance exercise improves the vascular function and decreases the blood pressure in rats. However, further studies are needed to better understand the effects of different resistance exercise protocols on the cardiovascular system.