Estudo da atividade antifúngica da associação do óleo essencial de Cymbopogon Winterianus Jowitt (Citronela) com antifúngicos sintéticos sobre espécies de Aspergillus

• Ano de defesa: 2010
• Autor(a) principal: Barbosa, Danilo Batista Martins
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal da Paraí­ba; BR; Odontologia; Programa de Pós Graduação em Odontologia; UFPB
• Palavras-chave em Português: Aspergillus; Cymbopogon; Fitoterapia; Óleo essencial; Agentes Antifúngicos; Phytotherapy; Volatile Oils; Antifungal Agents; CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
• Link de acesso: https://repositorio.ufpb.br/jspui/handle/tede/6632

This research aimed to study the antifungal properties of essential oil of Cymbopogon winterianus Jowitt associated with synthetic antifungals against strains of Aspergillus. The parameters used for this purpose were based on the determination of Minimum Inhibitory Concentration, Fractional Inhibitory Concentration Index (method of association - Checkerboard) as well as in microbial death curve. Amphotericin B and fluconazole antifungal synthetic were used as positive controls, and is also used in combination with tests of the natural product. All tests were performed in triplicate. The present study allowed further our understanding about the therapeutic effects of essential oil of C. winterianus, when used in isolation or drug related alluded to earlier. In addition, we attempted to find viable alternatives to the treatment of Aspergillus infections, currently based on the prolonged use of allopathic drugs, where the observed side effects are a limiting factor to its full success.