Novos flavonóides monoterpênicos e outros constituintes químicos isolados de espécies de Piper(PIPERACEAE)
Ano de defesa: | 2008 |
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Autor(a) principal: | |
Orientador(a): | |
Banca de defesa: | |
Tipo de documento: | Tese |
Tipo de acesso: | Acesso aberto |
Idioma: | por |
Instituição de defesa: |
Universidade Federal da Paraíba
BR Farmacologia Programa de Pós-Graduação em Produtos Naturais e Sintéticos Bioativos UFPB |
Programa de Pós-Graduação: |
Não Informado pela instituição
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Departamento: |
Não Informado pela instituição
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País: |
Não Informado pela instituição
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Palavras-chave em Português: | |
Link de acesso: | https://repositorio.ufpb.br/jspui/handle/tede/6690 |
Resumo: | Piper montealegreanum Yuncker, Piper carniconnectivum C.DC. and Piper glandulosissimum Yuncker are small shrubs of Piperaceae family native of Amazonian region. The use of this plant in folk medicine is still unknown. There are only a few studies regarding chemical and pharmacological studies of this species. In a previous study from the aerial parts of Piper montealegreanum were isolated two unpublished flavonoids and their mixture presented spasmolytic effect in aorta and trachea rings of rats and guinea-pig, respectively. (ALVES, 2004). In this work we continued the phytochemistry studies with plant and isolated five compounds: two new flavonoids, two phenylalkanoids unpublished and one phaeophytin. From Piper carniconnectivum were already isolated ciclopentanodiones and some flavonoids (FACUNDO et al, 2003 e 2004). In our research we isolated three flavonoids (two isolated for the time first in the genus), one new benzoic acid derivative, one cerid with its first report in the family, two steroids and a phaeophytin a. From Piper glandulosissimum (SANTOS, 2004) a flavonoid was isolated. They structures of the compounds were established by spectroscopic analyses (UV, IR, MS and 1H, 13C NMR, including 2D NMR), besides comparison with scientific literature. |