SAÚDE BUCAL DE CRIANÇAS E ADOLESCENTES COM PARALISIA CEREBRAL: ASPECTOS CLÍNICOS E BIOQUÍMICOS

Detalhes bibliográficos
Ano de defesa: 2018
Autor(a) principal: Malta, Cristiana Pereira
Orientador(a): Bento, Leticia Westphalen
Banca de defesa: Barcelos, Cristine Silva, Antoniazzi, Raquel Pippi
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Franciscana
Programa de Pós-Graduação: Mestrado em Ciências da Saúde e da Vida
Departamento: Ciências da Saúde e da Vida
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: http://www.tede.universidadefranciscana.edu.br:8080/handle/UFN-BDTD/612
Resumo: The aim of this study was to evaluate the clinical and biochemical aspects of the oral conditions of children and adolescents with cerebral palsy (CP), comparing this with patients with typical development, and to associate the clinical circumstances with the caregivers’ perception regarding oral health. This cross-sectional study occurred from March to September 2017. The study group consisted of 35 children and adolescents of both sexes, with clinical diagnosis of PC and age between 2 and 20 years. The control group consisted of 35 individuals with typical development, paired to the study group for age, sex and caries activity. A questionnaire was administered to caregivers with questions related to the oral health of the individuals under their care. The clinical examination included: caries activity, dmft/DMFT index, visible plaque index (VPI) and occlusal characteristics. The non-stimulated total saliva was collected through a special sterile polypropylene tube associated to the sucker of the dental equipment. Saliva was used to assess pH, buffer capacity and oxidative status. A total of 57.2% of children and adolescents with CP had experience of caries. The mean dmft/DMFT of the study group was 2.77±3.20. Regarding the perception of the caregivers, there were statistically significant differences between the groups, in the perception of problems in the teeth (p = 0.004) and gingival bleeding (p = 0.013). Class II molar relation, overjet and anterior open bite were more prevalent in children and adolescents with CP. CP was related to lower salivary pH, higher IPV, higher salivary levels of reactive species and lipid peroxidation. In addition, CP was able to modulate salivary levels of non-enzymatic antioxidants such as reduced glutathione (GSH) and vitamin C (VIT C). It can be concluded that caregivers of people with CP reported perceiving more problems in oral health, such as visible biofilm, gingival bleeding and malocclusion, than caregivers of children with typical development. In addition, CP was associated with lower salivary pH, higher IPV, higher oxidative status, and modulated the endogenous antioxidant defense system of saliva.