Detalhes bibliográficos
| Ano de defesa: |
2021 |
| Autor(a) principal: |
Augé, Luciana Barros |
| Orientador(a): |
Krause, Luciana Fontanari |
| Banca de defesa: |
Scapini, Fabrício,
Peroza, Luis Ricardo |
| Tipo de documento: |
Dissertação
|
| Tipo de acesso: |
Acesso aberto |
| Idioma: |
por |
| Instituição de defesa: |
Universidade Franciscana
|
| Programa de Pós-Graduação: |
Mestrado em Ciências da Saúde e da Vida
|
| Departamento: |
Ciências da Saúde e da Vida
|
| País: |
Brasil
|
| Palavras-chave em Português: |
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| Palavras-chave em Inglês: |
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| Área do conhecimento CNPq: |
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| Link de acesso: |
http://www.tede.universidadefranciscana.edu.br:8080/handle/UFN-BDTD/985
|
Resumo: |
Human papillomavirus (HPV) is a microorganism that has the potential to infect the skin and mucous membranes, causing local tissue injury or remaining asymptomatic. When one’s immune system is not capable of fighting an invasion of the virus, it remains latent inside the nucleus of infected cells. One of the clinical manifestations is the presence of benign epithelial lesions in the oral cavity, which include squamous cell papilloma, common skin warts, focal epithelial hyperplasia and papillary hyperplasia. Human papillomaviruses have an etiological role in cancers of the pharynx and the oral cavity, with 25-50% of cases being attributed to HPV infections. This study aims to study the prevalence of oral HPV, as well as the best technique for collecting and analyzing oral HPV. Prevalence of HPV oral infection among patients asymptomatic were 0% (0/3), and symptomatic were 25% (1/4). The paraffin block was positive for HPV, but the anatomopathological was negative. This study show anatomopathological may not be the best diagnostic method for HPV lesions. After papilloma resection, patients may be negative for oral HPV infection. It has been observed that the development of oropharyngeal cancer in a younger and non-smoking population could be attributable to HPV as an independent causal factor and has been a subject of increasing interest for the research community. HPV vaccination is expected to impact oral HPV incidence rates, leastwise for the genotypes included in the vaccine. |
