Avaliação da eficácia de diferentes drogas antiparasitárias contra Tunga penetrans em cães naturalmente infestados na região da Amazônia Meridional

• Ano de defesa: 2023
• Autor(a) principal: Nantes, José Dirceu Ferreira
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Mato Grosso; Brasil; Instituto de Ciências da Saúde (ICS) - Sinop; UFMT CUS - Sinop; Programa de Pós-Graduação em Ciências em Saúde
• Palavras-chave em Português: Tungíase; Sarolaner; Amazônia Meridional; CNPQ::CIENCIAS DA SAUDE::MEDICINA; Tungiasis; Southern Amazon
• Link de acesso: http://ri.ufmt.br/handle/1/5829

Tungiasis is a neglected dermatological condition caused by the penetration of the female flea Tunga penetrans into the skin of humans and different species of domestic and wild animals. After being fertilized by the male, which is usually related to the soles of people's feet and animal feet, the parasite expands at its penetration site, causing local hypertrophy due to the expansion of its abdominal segments. This study aims to evaluate the tungicidal efficacy of two antiparasitic formulations in infestations by Tunga penetrans in dogs in the southern Amazon region of Mato Grosso. A total of 48 animals were evaluated, divided into four groups. 12 animals were treated with Fipronil, 12 animals with Nitempiram, 12 animals with Sarolaner and 12 with Selamectin. All animals received the dose as recommended by the manufacturers. These were quantified at 3, 7 and 14 days post-treatment. According to the results, Fipronil showed lower efficacy on the 14th day after treatment, while the curative effect of Nitempiram was maximum on the third day after treatment (92.20%). The animals treated with Sarolaner showed better results than the other animals treated with the other three formulations. These animals had a 98.63% reduction in parasitism until the 14th day of evaluation. On the other hand, Selamectin reached efficacy above 90% only on the 14th day after treatment. Thus, only three formulations showed favorable results in the control of T. penetrans in naturally parasitized dogs.