Relação entre avaliação nutricional e escore prognóstico de Glasgow em pacientes com câncer de cólon e reto

• Ano de defesa: 2012
• Autor(a) principal: Silvia Fernandes Mauricio
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Minas Gerais; UFMG
• Palavras-chave em Português: Avaliação do Estado Nutricional; Escore Prognóstico de Glasgow; Complicações; Câncer; Nutrição Avaliação; Desnutrição Complicações e sequelas; Cólon Câncer
• Link de acesso: http://hdl.handle.net/1843/BUOS-8U3LY8

The relationship between weight loss and presence of inflammation has been described in cancer patients. Both nutritional status and severity of inflammation may be associated with lower response to treatment, occurrence of complications and decreased quality of life. Thus, the assessment of inflammation could be used as a tool to screen patients who may benefit from early nutritional interventions. In the present study we have assessed the relationship between nutritional status, defined by the Subjective Global Assessment (SGA), and the severity of inflammation defined by the Glasgow Prognostic Score (GPS). In addiction, we compared the diagnosis given by the SGA and the GPS groups with other parameters of nutritional assessment, such as body mass index (BMI), triceps skinfold (TSF), midarm circumference (MAC), midarm muscle circumference (MMAC), midarm muscle area (AMA), pollicis muscle thickness (APMT), hand grip strength (HGS) and phase angle (PA). These anthropometric indicators were also compared to PA and DM. This study enrolled 70 patients with colorectal cancer with a mean age of 60.4 ± 14.3 years. Nutritional status, according to the three categories of SGA was associated with the three categories of the EPG (p <0.05), but both were not associated with the presence of complications. Comparing the other methods of nutritional assessment with the AGS, significant differences were found. No statistically significant differences were seen when comparing these methods with the GPS. The PA was associated with stage, BMI, MAC, MMAC, AMA, APMT and percentage of weight loss as well as DM was only associated only with MMAC and percentage of weight loss. Independently of the methods, malnutrition was highly prevalence among patients with colorectal cancer.