Prevalência e fatores de risco de hiponatremia em lactentes com fibrose cística diagnosticados a partir da triagem neonatal

Detalhes bibliográficos
Ano de defesa: 2008
Autor(a) principal: Graziela Cristina Mattos Schettino
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Minas Gerais
UFMG
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: http://hdl.handle.net/1843/ECJS-7N4F7N
Resumo: Objective: infants with cystic fibrosis (CF) diagnosis present highersusceptibility to develop hydroelectrolitic disturbances, which may be fatal if they are not dealt with in time. Hyponatremia in this age group may be related to several factors such as high environmental temperatures, acute diarrhea, breast feeding, pulmonary infectious exacerbation. A major challenge in these hyponatremia cases is to carry out the appropriate prophylaxis. This revision purpose is to deal with the hyponatremy in CF, as well as its treatment and prevention. Data Sources: A non systematic review of the international medical literature was carried out through the sites Medline. The used descriptors were asfollows: cystic fibrosis, hyponatremia, metabolic alkalosis, pseudo-Bartter syndrome, all children under 18 years were selected as research limiters. Data synthesis: The prevalence of hyponatremia in fibrocystic patients varies according to the study geographic location, 16,2% to 75%. Most studies found in the literature describe cases of chronic hyponatremia complicated under the pseudo-Bartter syndrome (PSB). Authors recommended that all infants with CF must receive sodium oral replacement, mainly when in breastfeeding and in thehottest days. Conclusions: Hyponatremia in infants with FC is poorly described in the international medical literature. Althoug, the studies demonstrated hight prevalence of these complication, mainly in patients with less than 12 months of age.