Detalhes bibliográficos
| Ano de defesa: |
2015 |
| Autor(a) principal: |
REIS, Nayrana Soares do Carmo
 |
| Orientador(a): |
NINA, Vinícius José da Silva
|
| Banca de defesa: |
FIGUEIREDO NETO, José Albuquerque de
,
THOMAS, Erika Barbara Abreu Fonseca
,
BARBOSA, José Bonifácio
|
| Tipo de documento: |
Dissertação
|
| Tipo de acesso: |
Acesso aberto |
| Idioma: |
por |
| Instituição de defesa: |
Universidade Federal do Maranhão
|
| Programa de Pós-Graduação: |
PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE/CCBS
|
| Departamento: |
DEPARTAMENTO DE MEDICINA I/CCBS
|
| País: |
Brasil
|
| Palavras-chave em Português: |
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| Palavras-chave em Inglês: |
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| Área do conhecimento CNPq: |
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| Link de acesso: |
https://tedebc.ufma.br/jspui/handle/tede/2071
|
Resumo: |
INTRODUCTION: Some epidemiological studies have observed a close relationship between metabolic syndrome (MS) and the prevalence of chronic kidney disease (CKD) among different ethnic groups. African descent have a greater susceptibility to the development of these comorbidities. There is a lack of studies in this population group in Brazil, especially those living in quilombolas communities in socially vulnerable. OBJECTIVE: To evaluate the association between metabolic syndrome and its individuals components with chronic kidney disease in adults residing in quilomblas communities. METHODS: Study prospective, cross-sectional, populationbased, conducted in quilombolas communities in the municipality of Alcântara, Maranhão, Brazil. Data were collected demographic social and clinical, waist circumference, blood pressure and biological material for fasting glucose analysis, creatinine, HDL-cholesterol and triglycerides. The presence of MS was defined according to the harmonized criteria and the DRC determined by a glomerular filtration rate (GFR) <60 mL / min for a basal period and further three months. The estimated GFR was calculated from the formula of the Modification of Diet Renal Disease (MDRD). RESULTS: A total of 1514 subjects with a mean age of 44.3 ± 17.36 years and a predominance of females (51.3%). The prevalence of MS was 39.1%, with the majority of the study participants had altered values of waist circumference and blood pressure. The rate of kidney patients was found to be 1.7%, which showed higher average levels of blood pressure, body mass index, waist circumference, fasting glucose, and triglycerides (TG) (p <0.05). With the logistic regression model was no association between MS and CKD in unadjusted and adjusted analyzes for age and gender (p <0.05). Only the triglyceride (TG) remained significantly associated with the presence of CKD (p = 0.008) in multivariate adjusted analysis. CONCLUSION: Despite the low rate DRC, SM had high prevalence predominantly of components waist circumference and high blood pressure. In individuals with CKD was observed a significant increase in the mean values of all components of MS, except HDL-cholesterol. The presence of MS increased the risk for CKD, even when adjusted values for age and sex. However, only the TG component kept this association after multivariate adjustment. |
