PROLOTERAPIA UTILIZANDO GLICOSE HIPERTÔNICA NO TRATAMENTO DE DOR LOMBAR: ENSAIO CLÍNICO RANDOMIZADO

Detalhes bibliográficos
Ano de defesa: 2022
Autor(a) principal: PIRES, José Alberto Pereira lattes
Orientador(a): LEAL, Plínio da Cunha lattes
Banca de defesa: LEAL, Plínio da Cunha lattes, NASCIMENTO, Maria do Desterro Soares Brandão lattes, MOURA, Ed Carlos Rey lattes, MARQUES, Consuelo Penha Castro lattes
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal do Maranhão
Programa de Pós-Graduação: PROGRAMA DE PÓS-GRADUAÇÃO EM SAÚDE DO ADULTO
Departamento: DEPARTAMENTO DE MEDICINA I/CCBS
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: https://tedebc.ufma.br/jspui/handle/tede/4114
Resumo: Introduction: Chronic low back pain is pain that persists for more than three months and is one of the medical conditions with the most significant social impact, affecting 80% of adults. Objetive: To compare conservative therapy and prolotherapy with hypertonic glucose in chronic low back pain patients. Materials and methods: Cohort clinical trial, randomized, unblinded, with patients allocated into two groups, conservative therapy and 75% Hypertonic Glycemia, evaluated and followed up at the clinic "Oficina da Coluna" at the Macroregional Hospital, Pinheiro – MA. Results: Were included 19 patients in the Conservative group and 19 in the Glucose group, with a predominance of women (57.9%), aged between 47 and 59 years (39.5%), mixed-race (76.3%), married or in a stable relationship (73.7%), 5.2 years of study, mean BMI of 27.3±4.4 kg/m2, higher in the conservative group with 28.0±4.7 kg/m2, however, there was no significant difference (p-value = 0.938).. The groups showed differences concerning the Visual Analogue Scale, with median and amplitude close between the evaluated moments, increasing in the Glucose group, which, in the third evaluation, presented significantly higher values for this scale (p-value = 0.031). Comparing the groups on the Rolland-Morris scale, only in the 3m assessment was a significant difference, with a lower median observed in the conservative group (p-value = 0.021). Assessing the follow-up, both groups showed a significant improvement between T0 and the other evaluation moments, p- value < 0.05 in all evaluations. Conclusion: Both groups showed significant improvements during follow-up on the evaluated scales. Thus, prolotherapy was not more effective than the conservative approach. Overall, no effects were attributable to the glucose components and prolotherapy protocol.