Avaliação da exposição ao vírus chikungunya em população de Goiânia-Goiás

• Ano de defesa: 2019
• Autor(a) principal: Morais, Paulo Henrique de
• Orientador(a): Fiaccadori, Fabíola Souza
• Banca de defesa: Fiaccadori, Fabíola Souza, Souza, Menira Borges de Lima Dias e, Féres, Valéria Christina de Rezende
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Goiás
• Programa de Pós-Graduação: Programa de Pós-graduação em Biologia da Relação Parasito-Hospedeiro (IPTSP)
• Departamento: Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG)
• País: Brasil
• Palavras-chave em Português: Vírus chikungunya; População geral; Soroprevalência; Soroepidemiologia
• Palavras-chave em Inglês: Chikungunya virus; General population; Seroprevalence; Seroepidemiology
• Área do conhecimento CNPq: BIOLOGIA E FISIOLOGIA DOS MICROORGANISMOS::VIROLOGIA
• Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tede/9589

The Central-West region presents wide circulation of different arboviruses, such as Zika virus (ZIKV), Dengue virus (DENV) and Chikungunya virus (CHIKV). Chikungunya fever is a disease of sudden onset, transmitted by mosquito vectors, intermediate hosts of CHIKV. This pathology represents a significant health problem for the infected person, and the disease can cause symptoms that can be prolonged for more than two years, such as polyarthralgia and myalgias, requiring greater recovery care than other arboviruses. The present study aimed to investigate the seroepidemiological profile of chikungunya virus infection in the population of the city of Goiânia-GO, in the years 2016 and 2018. The study population consisted of 174 individuals attended by the public health network of the municipality, with a clinical picture suspected of CHIKV infection in the years 2016 and 2018. The collected serum samples were submitted to the enzyme-linked immunosorbent assay for the detection of specific antibodies against CHIKV class G (anti-CHIKV-IgG), using commercial kit. A global positivity index for CHIKV of 2.3% was identified. Of the individuals investigated, four cases of IgG marker positivity were identified, two male and two female, being described in both the symptomatic picture of fever, myalgia and multiple arthralgias. Studies evaluating seroprevalence for CHIKV infection are still scarce in the country and the data obtained in the present study demonstrate the need for continuous monitoring and investigation of the circulation of this agent in the region.