Uso da furazolidona no tratamento clínico de cães com leishmaniose tegumentar americana

• Ano de defesa: 2013
• Autor(a) principal: Barcellos, Márcio Paiva
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal do Espírito Santo; BR; Mestrado em Ciências Veterinárias; Centro de Ciências Agrárias e Engenharias; UFES; Programa de Pós-Graduação em Ciências Veterinárias
• Palavras-chave em Português: Dog deseases; Drug therapy; Nitrofurans; Nitrofuranos; Leishmania (V.) braziliensis; Terapia medicamentosa; Cão - doenças nitrofuranos; Leishmania; Cão - Doenças; Medicina Veterinária; 619
• Link de acesso: http://repositorio.ufes.br/handle/10/5860

American cutaneous leishmaniasis (ACL) is a widespread disease in several countries. As recommended by the Brazilian Ministry for Health, a treatment of animals is contraindicated. The aim of this study was to test the use of furazolidone (FZ) to treat lesions in dogs suffering from ACL. The study was conducted with nine dogs with lesions and the presence of ACL as confirmed by ELISA and PCR for biopsy and culture for Leishmania (V.) braziliensis. The drug was administered orally in a concentration of 20 mg / kg every twelve hours for seven days, in three steps with an interval of 10 days, accompanied by laboratory monitoring of hematological and biochemical patterns. A regression of the lesion was observed in seven animals. FZ has proven an effective drug in the remission of lesions in dogs with ACL injury