Fatores sociodemográficos, comportamentais e clínicos associados à sífilis em parturientes com recém-nascidos prematuros : um estudo de caso-controle

Detalhes bibliográficos
Ano de defesa: 2016
Autor(a) principal: Cunha, Carla Baroni
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal do Espírito Santo
BR
Mestrado em Doenças Infecciosas
Centro de Ciências da Saúde
UFES
Programa de Pós-Graduação em Doenças Infecciosas
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
61
Link de acesso: http://repositorio.ufes.br/handle/10/7162
Resumo: Background: Syphilis remains an importante public health problem. It is estimated that 2 million pregnant women are infected annually worldwide. Inadequate or lack of a treatment may have serious adverse outcomes such as prematurity, low birth weight, early pregnancy loss or neonatal death. Objective: To evaluate sociodemographic, behavioral and clinical factors for syphilis in pregnant women with premature newborns. Methods: A case-control study was carried out between June 2012 and June 2013. A total of 404 pregnant women in preterm birth were attended at University Hospital Cassiano Antonio Moraes (HUCAM) in Vitória/ES. Out of these 404 parturient women, 16 were diagnosed as positive for syphilis (cases), and 388 were negative for syphilis, and out of these, 64 were selected using the criteria of similarity by age and city of residence in order to make similar groups. Results: The maternal mean age was 24.01 years (SD = 7.36). Among the pregnant women tested positive for syphilis, 87.5% had eight or less years of study (p = 0.005); 68.8% were single (p = 0.009); 56.3% had the first sexual intercourse between 14 and 17 years old (p = 0.042); 81.2% of the fetuses were born alive (p = 0.052); 75.0% weighed between 1500 and 2499g (p = 0.006); and 37.5% of the pregnant women had meconium in the amniotic fluid (p = 0.003). For the control group, 51.6% had eight or more years of study; 68.8% were married; 53.1% had the first sexual intercourse between 14 and 17 years old; 96.9% of the fetuses were born alive; 35.9% weighed less than 1500g; and 93.8% of the pregnant women had amniotic fluid without meconium. Multivariate analysis showed significant association of syphilis with the presence of meconium in the amniotic fluid [OR 7.9 (95% CI: 1.30 - 47.98) p=0.025] for preterm birth. Conclusions: This study showed an association between the presence of meconium in the amniotic fluid and syphilis in cases of premature births attended at HUCAM. Furthermore, it should be emphasized the necessity of screening for syphilis in antenatal care, as recommended by the Health Ministry of Brazil, especially in cases of preterm delivery.