Relação entre eventos adversos na infância materna e o desenvolvimento infantil: revisão sistemática

• Ano de defesa: 2019
• Autor(a) principal: Ximenes, Renata de Barros Bruno
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Palavras-chave em Português: Experiências Adversas da Infância; Desenvolvimento Infantil; Revisão Sistemática
• Link de acesso: http://www.repositorio.ufc.br/handle/riufc/43370

Twenty years ago, it was conducted the first study to access Adverse Childhood Experiences (ACEs) and their relation to outcomes in adulthood. The effects of exposure to childhood trauma can also be transmitted to other generations. The systematic review (SR), therefore, is established to determine if there is a reliable association between maternal ACEs in childhood and altered child development. We conducted a systematic review according to the guidelines of the MOOSE (Meta-analysis of Observational Studies in Epidemiology) and the PRISMA-E (Preferred Reporting Items for Systematic review with a Focus on Health Equity). The protocol was register with PROSPERO #CRD42018111456. A comprehensive search strategy was conducted in the following databases, using PECOS strategy: MEDLINE, Embase, CINAHL, Web of Science, SCOPUS, LILACS, SciELO and OpenGrey. We included observational studies that showed offspring’s health outcomes (global development, cognitive, language, or brain architecture) from mothers exposed to adverse events up to 18 years of age. Only articles with summaries in English, Portuguese or Spanish and published in the last 20 years, from 01/01/1998 onwards, were considered. Six studies (5 cohort and 1 cross-sectional) were selected at the end. Risk of bias and quality of the studies were also be assessed (STROBE - Strengthening the Reporting of Observational Studies in Epidemiology), NOS – Newcastle-Ottawa Scale). SR identified that maternal ACEs were associated with a negative impact on global child development, altered brain structure, Attention Deficit Hyperactivity Disorder (ADHD), and with autism in the offspring.