Avaliação das propriedades químicas, térmicas e citotóxicas de filmes de colágeno incorporados com lignina Kraft fracionada

• Ano de defesa: 2019
• Autor(a) principal: Costa, Juliana Fernandes Sales
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Palavras-chave em Português: Reaproveitamento; Resíduos; Colágeno; Lignina
• Link de acesso: http://www.repositorio.ufc.br/handle/riufc/59940

Collagen is a biodegradable, with low antigenicity protein that makes up 30% of animal connective tissues, conferring properties such as elasticity and structural maintenance. It can be used from fish industry waste, thus contributing to sustainable development. It is widely applicable in the cosmetic and pharmaceutical sectors, standing out in the production of films, where it acts as a polymer matrix. Collagen-based films, however, have low thermal stability and are susceptible to degradation by reactive oxygen species (ROS), a fact that can be mediated from the insertion of substances with high economic stability and antioxidant action, such as examples, polyphenolic substances. In this context, the present work aims at the production of bonding films incorporated with different concentrations of lignin Kraft, a residual polyphenol of the paper industry. The lignin was fractionated in ethanol, using the soluble fraction for insertion into the films. The collagen used kept its triple structure intact after extraction, as shown in the circular dichroism (CD) data. The films containing lignin showed good thermal properties (TGA) and water vapor permeability (PVA), besides presenting antioxidant (DPPH and ABTS) and anti-UV activity. Regarding cytotoxicity, the degree of toxicity of the films was found to be dependent on the concentration of lignin present.