Contribuição ao conhecimento química de plantas do nordeste do Brasil: Bowdichia virgilioides H.B.K

• Ano de defesa: 1997
• Autor(a) principal: Gomes, Geovany Amorim
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Palavras-chave em Português: Química orgânica
• Link de acesso: http://www.repositorio.ufc.br/handle/riufc/47833

Bowdichia virgilioides H.B.K. is popularly known as "Sucupira" in the "Chapada do Araripe"- Ceará, where it was collected. Its trunk bark is used in folk medicine as astrigent, antidiarrheic and as general tonic. This work deseribes the phytochemical study of B. virgilioides roots. Chromatography analysis of several organic solvent extracts (hexane, ethyl acetate and methanol) yielded lupeol, 3,6-dimethoxy-6",6"-dimethylchromeno-(7,8,2",3")-flavone, 3,5,6-trimethoxyfurano-(7,8,2",3")-flavone and a mixture of formononetin and pseudobaptigenin; and identification of its volatile oil components, was performed. Catalytic hydrogenation of 3,6-dimethoxy-6",6"-dimethylchromeno-(7,8,2",3")-flavone yielded 2- cyclohexyl- 3,6-dimethoxy-6", 6"-dimethylchroman-(7,8,2",3")-chromone not previously described in the literature. The bibliographic survey showed that, execpt lupeol, alI isolated compounds from B. virgilioides have not been yet published for the genus and the 13C NMR data for 3,6-dimethoxy-6", 6"-dimethylchromeno-(7,8,2",3 ")-flavone and 3,5,6-trimethoxyfurano-(7,8,2",3")-flavone are described for the first time. The identification of the volatile constituents was accomplished by CGL/MS and comparison Kovat's index and mass spectra of compounds with data from a computer library, as well as visual comparison to published spectral data. The non volatile constituents were identified by spectrometric analysis mainly IR, MS, 1H and 13C NMR, including bidimensional NMR experiments and comparison to literature data.