Monitorização da farmacoterapia em recém-nascidos de extremo baixo peso em unidade de terapia intensiva neonatal

• Ano de defesa: 2015
• Autor(a) principal: Loureiro, Catarine Vitor
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Palavras-chave em Português: Recém-Nascido; Peso ao Nascer; Quimioterapia
• Link de acesso: http://www.repositorio.ufc.br/handle/riufc/13599

Birth weight related or not to prematurity is the leading factor in deter mining the individual neonate likely to survive and have normal growth and development. Newborns born at less than 1000g are termed as extremely low birth weight infants and generally have comorbidities that contribute to the worsening of their clinical condition. In recent years, significant improvements i n the care and monitoring of the evolution of newborns have ocurred. Among the professionals who have to add the health team in neonatal care, the clinical pharmacist has proven essential for monitoring and optimization of pharmacological therapy in neonat al units. This study aimed to monitoring the extremely low birth weight infants’ pharmacotherapy in neonatal intensive care unit in Fortaleza, Ceará, and evaluation by means of process and outcome indicators. This is a descriptive and exploratory study tha t design the clinical and pharmacotherapeutic profile of patients, maternal characteristics, as well as analysis of patients’ pharmacotherapy by clinical pharmacist, which detect ed drug related problems , descri bed and classifi e d pharmaceutical intervention s and carried out the analysis of the process using quality indicators. A total of 33 neonates were monitor ed during October 2013 to June 2014. In relation to clinical characteristics of newborns, 54.5% were female, had a mean gestational age of 26.7 weeks and mean birth weight 734 . 5g. The mean age of the mothers o f the infants was 25.4 years and prevailed cesarean delivery. The analysis of pharmacotherapy performed by Anatomical Therapeutic Chemical classification revealed a predominance of drugs group "bl ood and blood forming organ" and "anti - infectives for systemic use." 37 drug - related problems were detected , the most common being "non - standard medicine in the institution" (24.3%) and "wrong count of days ’ treatment with antimicrobial" (21.6%). Among the negative outcomes associated with pharmacotherapy, prevailed untreated health problem (40%) and quantitative ineffectiveness (32%). The most frequent pharmaceutical interventions carried out were "correction of day - count treatment" and "correction of dose " , both with 21.6%, and "correction of dosage" ( 16.2% ) being classified mostly as related to effectiveness and "very significant." Indicators described and proposed in the present study were efficient to evaluate the developed process and can be easily use d for comparisons between goals and creation of evaluation parameters for the service. This study was shown to be possible to perform the monitoring of extremely low birth weight infants’ pharmacotherapy , highlighting the role of the clinical pharmacist in the 10 resolution and prevention drug related problems , contributing to the achievement of a safe and effective drug therapy