Síndrome metabólica, estado nutricional e perfil lipídico em crianças

• Ano de defesa: 2009
• Autor(a) principal: Rechenchosky, Leandro
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Estadual de Maringá; Brasil; Programa de Pós-Graduação Associado em Educação Física - UEM/UEL; UEM; Maringá; Centro de Ciências da Saúde
• Palavras-chave em Português: Crianças - Síndrome metabólica; Crianças - Perfil lipídico; Obesidade infantil; Crianças - Estado nutricional; Dislipidemias; Ciências da Saúde; Educação Física
• Link de acesso: http://repositorio.uem.br:8080/jspui/handle/1/2241

The metabolic syndrome (MS) is a complex disorder represented by multiple cardiovascular risk factors. Some researches have already demonstrated the presence of MS in children and adolescents and the relationship with dyslipidemias, but, there are few epidemiological studies that investigated the MS and the lipidic profile in Brazilian children, especially those who have normal weight. Thus, this paper investigated the association between MS, nutritional status and lipidic profile in 385 children, of both gender, age between 7.0 to 9.9 years old and registered in public and private schools from Maringá/PR. The data collect was taken place between June and November of 2007 in the laboratory registered in the National Program of Quality Control of the Brazilian Society of Clinic Analysis in accordance with ISO 9001/2000, and involved social demographic information, as gender, birth date, collect date, school and grade; anthropometric measures of body mass, height and abdominal circumference; hemodynamic measures, as blood pressure; and measures of metabolic components as total cholesterol, HDL cholesterol, LDL cholesterol and triglycerides and glucose, after fasting 8 to 12 hours. Nutritional state classification was obtained in accordance to the proposal of Cole et al. (2000), through body mass index. For the MS classification the adopted criteria were proposed by the National Cholesterol Education Program´s Adult Treatment Panel III - NCEP/ATPIII (2001) modified for age by Cook et al. (2003). For the lipidic profile assessment the cutoff points recommended by the I Diretriz de Prevenção da Aterosclerose na Infância e na Adolescência da Sociedade Brasileira de Cardiologia were used. The data analysis was done using the following tests: Kolmogorov- Smirnov, Mann-Whitney, ANOVA one-way, Bonferroni and Games-Howell Post-hoc, Qui-Square and Fischer. The significance adopted was 5% (p<0,05).The anthropometric classification of the nutritional status has indicated that 72%, 18.4% and 9.6% of the children were normal weight, overweight and obesity, respectively. According to the used cutoff points, the MS prevalence was approximately 3%, however, when the analysis is done only with the children classified as obese, this proportion increased to 16.2%. Thus, significant association was verified between MS and the nutritional status, as well as the number of altered components and the nutritional status. From the MS components none of the children presented altered glycemia. About gender no association was verified with the MS. Likewise, it was not verified significant association between components of the lipidic profile and gender. Significant association between lipidic profile and the nutritional status was observed only for the triglycerides component. Elevated proportion (55.8%) of the total cholesterol was verified in this study, being that, children with normal weight and apparently healthy, 52.7% presented hypercholesterolemia. It is verified that from all children 30% did not present any disorder in the lipidic profile components, that is an high prevalence (~70%) of the children with dyslipidemias was verified in this study. Considering these information, it is concluded that MS, unfavorable nutritional status and inadequate lipidic profile are definitely present in children, indicating the importance of an early diagnosis and the adoption of primary prevention measures already in pediatric ages.