Detalhes bibliográficos
Ano de defesa: |
2012 |
Autor(a) principal: |
Cunha, Hilda Helena Souza da
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Orientador(a): |
Antonello, Ivan Carlos Ferreira
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Banca de defesa: |
Não Informado pela instituição |
Tipo de documento: |
Dissertação
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Tipo de acesso: |
Acesso aberto |
Idioma: |
por |
Instituição de defesa: |
Pontifícia Universidade Católica do Rio Grande do Sul
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Programa de Pós-Graduação: |
Programa de Pós-Graduação em Medicina e Ciências da Saúde
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Departamento: |
Faculdade de Medicina
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País: |
BR
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Palavras-chave em Português: |
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Área do conhecimento CNPq: |
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Link de acesso: |
http://tede2.pucrs.br/tede2/handle/tede/1708
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Resumo: |
Objective: To evaluate the association of maternal serum uric acid (UA) and proteinuria with clinical and demographic data of pregnant women with preeclampsia syndrome (PES) complicated by HELLP syndrome. Methods: One hundred and nine pregnant women were divided into two groups: group 1 - HELLP pregnant women with PES complicated by HELLP syndrome (n=64); group 2 PES pregnant women with PES but no HELLP syndrome (n=105). Results: Age, ethnicity, parity, delivery mode and perinatal mortality were not statistically different between groups. Systolic and diastolic blood pressure, protein to creatinine (P/C) ratio, uric acid, creatinine and maternal complications were statistically different between groups; values were higher and events, more frequent among pregnant women with HELLP syndrome. The newborns of pregnant women with HELLP syndrome were more premature, had a lower birth weight and a lower APGAR score. Conclusion: Uric acid equal to or higher than 6.0 gm/dL and P/C ratio equal to or higher than 5 were more frequent in gestations with HELLP syndrome, which suggests that elevated proteinuria and uric acid levels in pregnant women with PES may increase the chances of developing HELLP syndrome |