Efeito de diferentes intervenções para modificação do estilo de vida sobre aspectos clínicos e metabólicos envolvidos na síndrome metabólica

Detalhes bibliográficos
Ano de defesa: 2015
Autor(a) principal: Piovesan, Carla Haas lattes
Orientador(a): Bodanese, Luiz Carlos lattes
Banca de defesa: Não Informado pela instituição
Tipo de documento: Tese
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Pontifícia Universidade Católica do Rio Grande do Sul
Programa de Pós-Graduação: Programa de Pós-Graduação em Medicina e Ciências da Saúde
Departamento: Escola de Medicina
País: Brasil
Palavras-chave em Português:
Área do conhecimento CNPq:
Link de acesso: http://tede2.pucrs.br/tede2/handle/tede/7402
Resumo: Purpose: The aim was to verify the effects of different interventions for lifestyle modifications on the number of diagnosis criteria and clinical aspects involved in Metabolic Syndrome (MS). Methods: A randomized controlled clinical trial including 125 individuals from 30 to 59 years old with MS was conducted in the Rehabilitation Center of PUCRS. Individuals were randomized into three intervention groups: Standard Intervention (SI) – nonpharmalogical intervention recommended by the guidelines for clinical management of MS, considered the control group in this trial; Group Intervention (GI) – group lifestyle change implemented weekly by a multidisciplinary team; Individual Intervention (II) – outpatient care through weekly individual consultations performed by a multidisciplinary team. The outcomes studied include the modification of the number of diagnosis criteria for MS and other clinical parameters such as cardiovascular risk score, Castelli Index (CI) and insulin resistance index HOMA-IR. Each group was assessed at the beginning and at the end of the interventions (three months). Results: Seventy-two individuals concluded the intervention, among them: SI: 19, GI: 25, and II: 28. Groups GI and II presented significant decrease of body mass index, waist circumference, and systolic arterial pressure after three months. The number of diagnosis criteria for MS decreased significantly – 40% of the individuals did not meet the criteria for the clinical condition studied at the end of the intervention. The largest reduction occurred within group II, where 52% of the individuals presented less than three criteria. Regarding CI and HOMA-IR, both variables were significantly reduced (p < 0.05) in groups GI and II. Conclusion: The interventions proposed by this study reinforce that nonpharmacological strategies for changing lifestyle impact the reduction of cardiovascular risk factors involved in MS. They are also able to remove the population from this clinical condition by decreasing diagnosis criteria.