Detalhes bibliográficos
| Ano de defesa: |
2024 |
| Autor(a) principal: |
Barasch, Sandra Regina dos Santos
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| Orientador(a): |
Novaes, Beatriz Cavalcanti de Albuquerque Caiuby
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| Banca de defesa: |
Não Informado pela instituição |
| Tipo de documento: |
Dissertação
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| Tipo de acesso: |
Acesso embargado |
| Idioma: |
por |
| Instituição de defesa: |
Pontifícia Universidade Católica de São Paulo
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| Programa de Pós-Graduação: |
Programa de Pós-Graduação em Comunicação Humana e Saúde
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| Departamento: |
Faculdade de Ciências Humanas e da Saúde
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| País: |
Brasil
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| Palavras-chave em Português: |
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| Palavras-chave em Inglês: |
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| Área do conhecimento CNPq: |
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| Link de acesso: |
https://repositorio.pucsp.br/jspui/handle/handle/41468
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Resumo: |
Introduction. Recent research has demonstrated the cerebellum involvement in cognitive and affective functions, and particularly in issues related to neurodevelopment and the acquisition of cognitive, linguistic and socio-emotional skills with an impact on academic and social learning. Autism spectrum disorder (ASD), specific learning disorders (dyslexia) and attention deficit hyperactivity disorder (ADHD) are the main conditions studied with cerebellar involvement in their pathophysiology. Cerebellar Cognitive Affective Syndrome (CCAS) has been studied in the adult and children population, but it has been observed that the earlier the cerebellar lesion, the greater the clinical repercussions, suggesting a relevant role for the cerebellum in neurodevelopment. The similarity of this syndrome with the clinical manifestations of Developmental Language Disorder (DLD) makes us think of a possible cerebellar role in the pathophysiology of this disorder. For this reason, to better understand the role of the cerebellum in language disorders, we will map the clinical manifestations and main etiologies of this cerebellar cognitive syndrome in the child and adolescent population with a focus on language deficits and present clinical cases of language and malformations restricted to the cerebellum. Objective. To map the clinical manifestations of children and adolescents with CCS in the literature over the last 30 years and to present clinical cases of children and adolescents seen at a phoniatrics outpatient clinic with language deficits and cerebellum-restricted lesions. Methods. We will discuss two clinical cases of children with language deficits and isolated cerebellar lesions from the Phoniatrics Outpatient Clinic of the Leonil Crê Bortolosso Polyclinic in the municipality of Osasco who underwent an expanded phoniatric assessment aimed at cerebellar cognitive dysfunctions (language, visual-spatial and executive functions). A scoping review of the literature will also be carried out to map the clinical findings of CCAS in children and adolescents over the last 30 years. Results: The literature review included 75 articles that identified various etiologies for CCAS in this population: congenital malformations, tumors, infections, prematurity, hereditary ataxias, social deprivation and trauma. The set of deficits found obeys and goes beyond the limits described in this syndrome, and can manifest to varying degrees, but are more persistent and have important consequences for child development, as exemplified by the two cases described. Conclusion: CCAS exists in children and is caused by various etiologies. Sensitive tests targeting cerebellar functions are necessary for its diagnosis and rehabilitation. Its cognitive, affective and language repercussions are usually more persistent, compromising the patient's neurodevelopment and quality of life |
