Níveis de cortisol salivar, grau de estresse e de ansiedade em indivíduos com síndrome de ardência bucal

• Ano de defesa: 2006
• Autor(a) principal: Amenábar, José Miguel
• Orientador(a): Souza, Maria Antonieta Lopes de
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Pontifícia Universidade Católica do Rio Grande do Sul; Porto Alegre
• Palavras-chave em Português: ODONTOLOGIA; PATOLOGIA BUCAL; SÍNDROME DA ARDÊNCIA BUCAL; ESTRESSE; ANSIEDADE; ODONTOLOGIA - ASPECTOS PSICOLÓGICOS
• Link de acesso: http://hdl.handle.net/10923/433

Burning mouth syndrome is defined as a complex disease, characterized by manifestation of oral burning symptoms, in the presence of a clinically normal mucosa. Its etiology is unknown, however, psychological factors, such as anxiety and stress, have been suggested as possible etiological agents. Cortisol, also known as hydrocortisone, is the main hormone involved in the modulation of the stress system, and its association with this syndrome never was done. The objective of this study was to evaluate the levels of cortisol, stress and anxiety in patients with burning mouth syndrome. A case-control study was done, with a sample of 60 people divided in 2 groups: SAB, with diagnosis of the syndrome, and control, without any complaint of burning mouth. Anamnesis, oral examination, sialometry, application of Lipp’s Inventory of Stress Symptoms for Adults and Beck’s Anxiety Inventory, as well as three saliva samples from different periods of the day for cortisol analysis, and were done in every patient. Statistical difference for xerostomy was found on the SAB group, but, in both groups, the salivary flow rate was normal. No statistical differences were found on the anxiety or stress levels between the groups, however the salivary cortisol levels of the SAB group were statistically higher (p = 0,0008) when compared to the control group. It was also verified, that salivary cortisol levels above 11,30nmol/L/h showed an Odds Ratio of 4,0 [ 95%IC (1,37 - 11,70) ]. The results suggest that cortisol levels were positively associated with the presence of burning mouth syndrome.