Extração de cromenos a partir de Ageratum conyzoides L.: identificação química e modelagem matemática do processo

• Ano de defesa: 2015
• Autor(a) principal: Almeida, Patrícia Carvalho
• Orientador(a): Vargas, Rubem Mario Figueiro
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Pontifícia Universidade Católica do Rio Grande do Sul; Porto Alegre
• Palavras-chave em Português: EXTRAÇÃO SUPERCRÍTICA; DESTILAÇÃO; ÓLEOS ESSENCIAIS; ENGENHARIA DE MATERIAIS
• Link de acesso: http://hdl.handle.net/10923/7904

Extracts obtained from natural products have attracted the interest of pharmacological sector due to the chemical and biological properties. Therefore, in this work were studied the chromenes (precocene I and II) extraction processes, steam distillation and supercritical fluid extraction (SFE), from Ageratum conyzoides L. Essential oil was extracted by saturated steam at 1. 0, 1. 5, and 2. 0 bar and the supercritical fluid extractions were performed at 40ºC and 90, 120, 150, and 200 bar to obtain non-volatile extracts. The essential oils were analyzed by gas chromatography/mass spectroscopy while the non-volatile extracts composition was determined by high-performance liquid chromatography. The essential oil presented two major compounds, precocene I (28. 24 ± 2. 64%) and precocene II (28. 55 ± 2. 08%). At 90 bar, the SFE resulted in higher yield and selectivity for precocene I and II, which represent 65. 06% of extract. It was observed that the yield of chromenes varies according to pressure of SFE, however this behavior was not observed in the extracts obtained by steam distillation. A mathematical model was also used to simulate the processes and a good correlation was attained with the experimental data.