Estudo hematológico e bioquímico do sangue de rato sob ação do cádmio em função do sexo

• Ano de defesa: 2006
• Autor(a) principal: Alves, Vladimir Menezes
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade de Franca; Brasil; Pós-Graduação; Programa de Mestrado em Promoção de Saúde; UNIFRAN
• Palavras-chave em Português: Cádmio; Sangue; Rato; Macho; Fêmea; CNPQ::CIENCIAS BIOLOGICAS::BIOQUIMICA
• Link de acesso: https://repositorio.cruzeirodosul.edu.br/handle/123456789/525

Male and female Wistar rats were injected subcutaneously with CdCl² in order to study hematologically and biochemically the effects of cadmium in the blood. During the eight days after the administration of 0.4 mg / ml / day of CdCl², the following events occurred: 1) body weight was reduced; 2) cadmium reduced the total number of erythrocytes, the hemoglobin content, the hematocrit and the percentage of lymphocytes; on the other hand, the total number of leukocytes and the percentage of neutrophils in females increased; 3) CdCl² increased the percentage of neutrophils and decreased the percentage of lymphocytes in males; 4) there was an increase in aspartate aminotransferase and bilirubin, in addition to a decrease in creatinine in females; 5) in males there was a decrease in alkaline phosphatase and cholesterol. In the conditions of this study, the most evident changes were observed in the females treated with CdCl².