Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge
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| Auteur principal: | |
|---|---|
| Date de publication: | 2020 |
| Format: | Article |
| Langue: | eng |
| Source: | Repositório Institucional da UnB |
| Download full: | https://repositorio.unb.br/handle/10482/39845 https://doi.org/10.1590/0037-8682-0669-2020 http://orcid.org/0000-0001-6586-2662 |
Résumé: | In the absence of vaccines and effective antiviral drugs, control of the spread of coronavirus disease (Covid-19) relies mainly on the adequacy of public health resources and policies. Hence, failure to establish and implement scientifically reliable control measures may have a significant effect on the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, severity of the disease, and death toll. The average number of secondary transmissions from an infected person, or reproduction numbers (R0 and R), and the points at which the collective immunity begins to reduce the transmission of the infection, or herd immunity thresholds, are important epidemiological tools used in strategies of Covid-19 control, suppression, and mitigation. However, SARS-CoV-2 transmission through asymptomatic carriers and, possibly, aerosols, has been ignored, and this may affect the effectiveness of Covid-19 control strategies. Therefore, consideration of the two possible ways of transmission would substantially increase the values of reproduction numbers, but if estimates of the contingent of the population naturally resistant to the virus, plus those with pre-existing cross-immunity to SARS-CoV-2 were considered, the evaluation of herd immunity thresholds should reach their real and achievable levels. |
| _version_ | 1871442600478638080 |
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| author | Tosta, Carlos Eduardo |
| author_browse | Tosta, Carlos Eduardo |
| author_facet | Tosta, Carlos Eduardo |
| author_role | author |
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| bitstream.url.fl_str_mv | http://repositorio.unb.br/bitstream/10482/39845/1/ARTIGO_TransmissionSevereAcute.pdf http://repositorio.unb.br/bitstream/10482/39845/2/license.txt |
| collection | Repositório Institucional da UnB |
| dc.contributor.author.fl_str_mv | Tosta, Carlos Eduardo |
| dc.date.accessioned.fl_str_mv | 2020-12-31T17:06:23Z |
| dc.date.available.fl_str_mv | 2020-12-31T17:06:23Z |
| dc.date.issued.fl_str_mv | 2020 |
| dc.identifier.citation.fl_str_mv | TOSTA, Eduardo. Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols: a major public health challenge. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 53, e20200669, 2020. DOI: https://doi.org/10.1590/0037-8682-0669-2020. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100212&lng=en&nrm=iso. Acesso em: 31 dez. 2020. Epub Dec 11, 2020. |
| dc.identifier.doi.pt_BR.fl_str_mv | https://doi.org/10.1590/0037-8682-0669-2020 |
| dc.identifier.orcid.pt_BR.fl_str_mv | http://orcid.org/0000-0001-6586-2662 |
| dc.identifier.uri.fl_str_mv | https://repositorio.unb.br/handle/10482/39845 |
| dc.language.iso.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Sociedade Brasileira de Medicina Tropical - SBMT |
| dc.rights.driver.fl_str_mv | OPEN ACCESS https://creativecommons.org/licenses/by/4.0/. info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:Repositório Institucional da UnB instname:Universidade de Brasília (UnB) instacron:UNB |
| dc.subject.keyword.pt_BR.fl_str_mv | SARS-CoV-2 Covid-19 Infecção por coronavírus - transmissão Portador assintomático Transmissão aerotransportada |
| dc.title.pt_BR.fl_str_mv | Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge |
| dc.type.driver.fl_str_mv | info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv | info:eu-repo/semantics/publishedVersion |
| description | In the absence of vaccines and effective antiviral drugs, control of the spread of coronavirus disease (Covid-19) relies mainly on the adequacy of public health resources and policies. Hence, failure to establish and implement scientifically reliable control measures may have a significant effect on the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, severity of the disease, and death toll. The average number of secondary transmissions from an infected person, or reproduction numbers (R0 and R), and the points at which the collective immunity begins to reduce the transmission of the infection, or herd immunity thresholds, are important epidemiological tools used in strategies of Covid-19 control, suppression, and mitigation. However, SARS-CoV-2 transmission through asymptomatic carriers and, possibly, aerosols, has been ignored, and this may affect the effectiveness of Covid-19 control strategies. Therefore, consideration of the two possible ways of transmission would substantially increase the values of reproduction numbers, but if estimates of the contingent of the population naturally resistant to the virus, plus those with pre-existing cross-immunity to SARS-CoV-2 were considered, the evaluation of herd immunity thresholds should reach their real and achievable levels. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | UNB_ee69ce163a6fab4c3b2dfa05e8a6cfce |
| identifier_str_mv | TOSTA, Eduardo. Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols: a major public health challenge. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 53, e20200669, 2020. DOI: https://doi.org/10.1590/0037-8682-0669-2020. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100212&lng=en&nrm=iso. Acesso em: 31 dez. 2020. Epub Dec 11, 2020. |
| instacron_str | UNB |
| institution | UNB |
| instname_str | Universidade de Brasília (UnB) |
| language | eng |
| network_acronym_str | UNB |
| network_name_str | Repositório Institucional da UnB |
| oai_identifier_str | oai:repositorio.unb.br:10482/39845 |
| publishDate | 2020 |
| publishDateSort | 2020 |
| publisher.none.fl_str_mv | Sociedade Brasileira de Medicina Tropical - SBMT |
| reponame_str | Repositório Institucional da UnB |
| repository.mail.fl_str_mv | repositorio@unb.br |
| repository.name.fl_str_mv | Repositório Institucional da UnB - Universidade de Brasília (UnB) |
| repository_id_str | |
| rights_invalid_str_mv | OPEN ACCESS https://creativecommons.org/licenses/by/4.0/. |
| spelling | Tosta, Carlos Eduardo2020-12-31T17:06:23Z2020-12-31T17:06:23Z2020TOSTA, Eduardo. Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols: a major public health challenge. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 53, e20200669, 2020. DOI: https://doi.org/10.1590/0037-8682-0669-2020. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100212&lng=en&nrm=iso. Acesso em: 31 dez. 2020. Epub Dec 11, 2020.https://repositorio.unb.br/handle/10482/39845https://doi.org/10.1590/0037-8682-0669-2020http://orcid.org/0000-0001-6586-2662Sociedade Brasileira de Medicina Tropical - SBMTOPEN ACCESS https://creativecommons.org/licenses/by/4.0/.info:eu-repo/semantics/openAccessTransmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challengeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleSARS-CoV-2Covid-19Infecção por coronavírus - transmissãoPortador assintomáticoTransmissão aerotransportadaIn the absence of vaccines and effective antiviral drugs, control of the spread of coronavirus disease (Covid-19) relies mainly on the adequacy of public health resources and policies. Hence, failure to establish and implement scientifically reliable control measures may have a significant effect on the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, severity of the disease, and death toll. The average number of secondary transmissions from an infected person, or reproduction numbers (R0 and R), and the points at which the collective immunity begins to reduce the transmission of the infection, or herd immunity thresholds, are important epidemiological tools used in strategies of Covid-19 control, suppression, and mitigation. However, SARS-CoV-2 transmission through asymptomatic carriers and, possibly, aerosols, has been ignored, and this may affect the effectiveness of Covid-19 control strategies. Therefore, consideration of the two possible ways of transmission would substantially increase the values of reproduction numbers, but if estimates of the contingent of the population naturally resistant to the virus, plus those with pre-existing cross-immunity to SARS-CoV-2 were considered, the evaluation of herd immunity thresholds should reach their real and achievable levels.Faculdade de Medicina (FM)engreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNBORIGINALARTIGO_TransmissionSevereAcute.pdfARTIGO_TransmissionSevereAcute.pdfapplication/pdf932056http://repositorio.unb.br/bitstream/10482/39845/1/ARTIGO_TransmissionSevereAcute.pdf298d03f44c3d24c80ea6d167d564690aMD51open accessLICENSElicense.txtlicense.txttext/plain163http://repositorio.unb.br/bitstream/10482/39845/2/license.txtba54f8d1c5f5ec8df897ad678916c701MD52open access10482/398452025-01-15 15:13:04.367open accessoai:repositorio.unb.br:10482/39845U3VibWlzc8OjbyBlZmV0aXZhZGEgcG9yIGludGVncmFudGUgZGEgZXF1aXBlIGRvIFJlcG9zaXTDs3JpbyBJbnN0aXR1Y2lvbmFsIGRhIFVuQiBkZSBhY29yZG8gY29tIGxpY2Vuw6dhIGNvbmNlZGlkYSBwZWxvIGF1dG9yIGUvb3UgZGV0ZW50b3IgZG9zIGRpcmVpdG9zIGF1dG9yYWlzLg==Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2025-01-15T18:13:04Repositório Institucional da UnB - Universidade de Brasília (UnB) |
| spellingShingle | Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge Tosta, Carlos Eduardo SARS-CoV-2 Covid-19 Infecção por coronavírus - transmissão Portador assintomático Transmissão aerotransportada |
| status_str | publishedVersion |
| title | Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge |
| title_full | Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge |
| title_fullStr | Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge |
| title_full_unstemmed | Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge |
| title_short | Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge |
| title_sort | Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge |
| topic | SARS-CoV-2 Covid-19 Infecção por coronavírus - transmissão Portador assintomático Transmissão aerotransportada |
| url | https://repositorio.unb.br/handle/10482/39845 https://doi.org/10.1590/0037-8682-0669-2020 http://orcid.org/0000-0001-6586-2662 |