Genus Paracoccidioides : species recognition and biogeographic aspects
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| Data de publicació: | 2012 |
| Altres autors: | , , , , , |
| Format: | Article |
| Idioma: | eng |
| Font: | Repositório Institucional da UnB |
| Download full: | http://repositorio.unb.br/handle/10482/12625 https://dx.doi.org/10.1371/journal.pone.0037694 |
Sumari: | Background: Paracoccidioidomycosis is a systemic mycosis caused by Paracoccidioides brasiliensis (species S1, PS2, PS3), and Paracoccidioides lutzii. This work aimed to differentiate species within the genus Paracoccidioides, without applying multilocus sequencing, as well as to obtain knowledge of the possible speciation processes. Methodology/Principal Findings: Single nucleotide polymorphism analysis on GP43, ARF and PRP8 intein genes successfully distinguished isolates into four different species. Morphological evaluation indicated that elongated conidia were observed exclusively in P. lutzii isolates, while all other species (S1, PS2 and PS3) were indistinguishable. To evaluate the biogeographic events that led to the current geographic distribution of Paracoccidioides species and their sister species, Nested Clade and Likelihood Analysis of Geographic Range Evolution (LAGRANGE) analyses were applied. The radiation of Paracoccidioides started in northwest South America, around 11–32 million years ago, as calculated on the basis of ARF substitution rate, in the BEAST program. Vicariance was responsible for the divergence among S1, PS2 and P. lutzii and a recent dispersal generated the PS3 species, restricted to Colombia. Taking into account the ancestral areas revealed by the LAGRANGE analysis and the major geographic distribution of L. loboi in the Amazon basin, a region strongly affected by the Andes uplift and marine incursions in the Cenozoic era, we also speculate about the effect of these geological events on the vicariance between Paracoccidioides and L. loboi. Conclusions/Significance: The use of at least 3 SNPs, but not morphological criteria, as markers allows us to distinguish among the four cryptic species of the genus Paracoccidioides. The work also presents a biogeographic study speculating on how these species might have diverged in South America, thus contributing to elucidating evolutionary aspects of the genus Paracoccidioides. |
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|---|---|
| author | Theodoro, Raquel Cordeiro |
| author2 | Teixeira, Marcus de Melo Felipe, Maria Sueli Soares Paduan, Karina dos Santos Ribolla, Paulo Martins San-Blas, Gioconda Bagagli, Eduardo |
| author2_role | author author author author author author |
| author_browse | Bagagli, Eduardo Felipe, Maria Sueli Soares Paduan, Karina dos Santos Ribolla, Paulo Martins San-Blas, Gioconda Teixeira, Marcus de Melo Theodoro, Raquel Cordeiro |
| author_facet | Theodoro, Raquel Cordeiro Teixeira, Marcus de Melo Felipe, Maria Sueli Soares Paduan, Karina dos Santos Ribolla, Paulo Martins San-Blas, Gioconda Bagagli, Eduardo |
| author_role | author |
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| bitstream.url.fl_str_mv | http://repositorio2.unb.br/jspui/bitstream/10482/12625/1/ARTIGO_GenusParacoccidioidesSpecies.pdf http://repositorio2.unb.br/jspui/bitstream/10482/12625/2/license.txt http://repositorio2.unb.br/jspui/bitstream/10482/12625/3/ARTIGO_GenusParacoccidioidesSpecies.pdf.txt |
| collection | Repositório Institucional da UnB |
| dc.contributor.author.fl_str_mv | Theodoro, Raquel Cordeiro Teixeira, Marcus de Melo Felipe, Maria Sueli Soares Paduan, Karina dos Santos Ribolla, Paulo Martins San-Blas, Gioconda Bagagli, Eduardo |
| dc.date.accessioned.fl_str_mv | 2013-03-27T19:40:26Z |
| dc.date.available.fl_str_mv | 2013-03-27T19:40:26Z |
| dc.date.issued.fl_str_mv | 2012-05 |
| dc.identifier.citation.fl_str_mv | THEODORO, Raquel Cordeiro et al. Genus paracoccidioides: species recognition and biogeographic aspects. Plos One, v. 7, n. 5, maio 2012. Disponível em: <http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037694>. Acesso em: 21 mar. 2013. DOI: 10.1371/journal.pone.0037694. |
| dc.identifier.doi.en.fl_str_mv | https://dx.doi.org/10.1371/journal.pone.0037694 |
| dc.identifier.uri.fl_str_mv | http://repositorio.unb.br/handle/10482/12625 |
| dc.language.iso.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | PLOS |
| dc.rights.driver.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:Repositório Institucional da UnB instname:Universidade de Brasília (UnB) instacron:UNB |
| dc.subject.keyword.en.fl_str_mv | Paracoccidioides brasiliensis Paracoccidioidomicose Fungos patogênicos |
| dc.title.en.fl_str_mv | Genus Paracoccidioides : species recognition and biogeographic aspects |
| dc.type.driver.fl_str_mv | info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv | info:eu-repo/semantics/publishedVersion |
| description | Background: Paracoccidioidomycosis is a systemic mycosis caused by Paracoccidioides brasiliensis (species S1, PS2, PS3), and Paracoccidioides lutzii. This work aimed to differentiate species within the genus Paracoccidioides, without applying multilocus sequencing, as well as to obtain knowledge of the possible speciation processes. Methodology/Principal Findings: Single nucleotide polymorphism analysis on GP43, ARF and PRP8 intein genes successfully distinguished isolates into four different species. Morphological evaluation indicated that elongated conidia were observed exclusively in P. lutzii isolates, while all other species (S1, PS2 and PS3) were indistinguishable. To evaluate the biogeographic events that led to the current geographic distribution of Paracoccidioides species and their sister species, Nested Clade and Likelihood Analysis of Geographic Range Evolution (LAGRANGE) analyses were applied. The radiation of Paracoccidioides started in northwest South America, around 11–32 million years ago, as calculated on the basis of ARF substitution rate, in the BEAST program. Vicariance was responsible for the divergence among S1, PS2 and P. lutzii and a recent dispersal generated the PS3 species, restricted to Colombia. Taking into account the ancestral areas revealed by the LAGRANGE analysis and the major geographic distribution of L. loboi in the Amazon basin, a region strongly affected by the Andes uplift and marine incursions in the Cenozoic era, we also speculate about the effect of these geological events on the vicariance between Paracoccidioides and L. loboi. Conclusions/Significance: The use of at least 3 SNPs, but not morphological criteria, as markers allows us to distinguish among the four cryptic species of the genus Paracoccidioides. The work also presents a biogeographic study speculating on how these species might have diverged in South America, thus contributing to elucidating evolutionary aspects of the genus Paracoccidioides. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | UNB_d18a32d29ea2b58a9e784474fba0e2cf |
| identifier_str_mv | THEODORO, Raquel Cordeiro et al. Genus paracoccidioides: species recognition and biogeographic aspects. Plos One, v. 7, n. 5, maio 2012. Disponível em: <http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037694>. Acesso em: 21 mar. 2013. DOI: 10.1371/journal.pone.0037694. |
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| instname_str | Universidade de Brasília (UnB) |
| language | eng |
| network_acronym_str | UNB |
| network_name_str | Repositório Institucional da UnB |
| oai_identifier_str | oai:repositorio.unb.br:10482/12625 |
| publishDate | 2012 |
| publishDateSort | 2012 |
| publisher.none.fl_str_mv | PLOS |
| reponame_str | Repositório Institucional da UnB |
| repository.mail.fl_str_mv | repositorio@unb.br |
| repository.name.fl_str_mv | Repositório Institucional da UnB - Universidade de Brasília (UnB) |
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| spelling | Theodoro, Raquel CordeiroTeixeira, Marcus de MeloFelipe, Maria Sueli SoaresPaduan, Karina dos SantosRibolla, Paulo MartinsSan-Blas, GiocondaBagagli, Eduardo2013-03-27T19:40:26Z2013-03-27T19:40:26Z2012-05THEODORO, Raquel Cordeiro et al. Genus paracoccidioides: species recognition and biogeographic aspects. Plos One, v. 7, n. 5, maio 2012. Disponível em: <http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037694>. Acesso em: 21 mar. 2013. DOI: 10.1371/journal.pone.0037694.http://repositorio.unb.br/handle/10482/12625https://dx.doi.org/10.1371/journal.pone.0037694Background: Paracoccidioidomycosis is a systemic mycosis caused by Paracoccidioides brasiliensis (species S1, PS2, PS3), and Paracoccidioides lutzii. This work aimed to differentiate species within the genus Paracoccidioides, without applying multilocus sequencing, as well as to obtain knowledge of the possible speciation processes. Methodology/Principal Findings: Single nucleotide polymorphism analysis on GP43, ARF and PRP8 intein genes successfully distinguished isolates into four different species. Morphological evaluation indicated that elongated conidia were observed exclusively in P. lutzii isolates, while all other species (S1, PS2 and PS3) were indistinguishable. To evaluate the biogeographic events that led to the current geographic distribution of Paracoccidioides species and their sister species, Nested Clade and Likelihood Analysis of Geographic Range Evolution (LAGRANGE) analyses were applied. The radiation of Paracoccidioides started in northwest South America, around 11–32 million years ago, as calculated on the basis of ARF substitution rate, in the BEAST program. Vicariance was responsible for the divergence among S1, PS2 and P. lutzii and a recent dispersal generated the PS3 species, restricted to Colombia. Taking into account the ancestral areas revealed by the LAGRANGE analysis and the major geographic distribution of L. loboi in the Amazon basin, a region strongly affected by the Andes uplift and marine incursions in the Cenozoic era, we also speculate about the effect of these geological events on the vicariance between Paracoccidioides and L. loboi. Conclusions/Significance: The use of at least 3 SNPs, but not morphological criteria, as markers allows us to distinguish among the four cryptic species of the genus Paracoccidioides. The work also presents a biogeographic study speculating on how these species might have diverged in South America, thus contributing to elucidating evolutionary aspects of the genus Paracoccidioides.PLOS© 2012 Theodoro etal.This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Fonte: http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037694. Acesso em: 21 mar. 2013.info:eu-repo/semantics/openAccessGenus Paracoccidioides : species recognition and biogeographic aspectsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleParacoccidioides brasiliensisParacoccidioidomicoseFungos patogênicosengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNBORIGINALARTIGO_GenusParacoccidioidesSpecies.pdfARTIGO_GenusParacoccidioidesSpecies.pdfapplication/pdf460462http://repositorio2.unb.br/jspui/bitstream/10482/12625/1/ARTIGO_GenusParacoccidioidesSpecies.pdf440a006a1259be9647de79400a99a6e2MD51open accessLICENSElicense.txtlicense.txttext/plain257http://repositorio2.unb.br/jspui/bitstream/10482/12625/2/license.txtffa4ebb88db13f2ff519a9fc8ad44975MD52open accessTEXTARTIGO_GenusParacoccidioidesSpecies.pdf.txtARTIGO_GenusParacoccidioidesSpecies.pdf.txtExtracted texttext/plain68062http://repositorio2.unb.br/jspui/bitstream/10482/12625/3/ARTIGO_GenusParacoccidioidesSpecies.pdf.txt304e07fff244d0033fee1d93d1bbf239MD53open access10482/126252023-05-24 20:34:32.687open accessoai:repositorio.unb.br:10482/12625TGljZW5zZSBncmFudGVkIGJ5IFJpY2FyZG8gVGF2YXJlcyAocmljYXJkb3NvYXJlc0BiY2UudW5iLmJyKSBvbiAyMDEzLTAzLTIxVDIwOjUyOjE4WiAoR01UKToKClN1Ym1pc3PDo28gZWZldGl2YWRhIHBvciBpbnRlZ3JhbnRlIGRhIGVxdWlwZSBkbyBSZXBvc2l0w7NyaW8gSW5zdGl0dWNpb25hbCBkYSBVbkIgZGUgYWNvcmRvIGNvbSBsaWNlbsOnYSBjb25jZWRpZGEgcGVsbyBhdXRvciBlL291IGRldGVudG9yIGRvcyBkaXJlaXRvcyBhdXRvcmFpcy4=Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2023-05-24T23:34:32Repositório Institucional da UnB - Universidade de Brasília (UnB) |
| spellingShingle | Genus Paracoccidioides : species recognition and biogeographic aspects Theodoro, Raquel Cordeiro Paracoccidioides brasiliensis Paracoccidioidomicose Fungos patogênicos |
| status_str | publishedVersion |
| title | Genus Paracoccidioides : species recognition and biogeographic aspects |
| title_full | Genus Paracoccidioides : species recognition and biogeographic aspects |
| title_fullStr | Genus Paracoccidioides : species recognition and biogeographic aspects |
| title_full_unstemmed | Genus Paracoccidioides : species recognition and biogeographic aspects |
| title_short | Genus Paracoccidioides : species recognition and biogeographic aspects |
| title_sort | Genus Paracoccidioides : species recognition and biogeographic aspects |
| topic | Paracoccidioides brasiliensis Paracoccidioidomicose Fungos patogênicos |
| url | http://repositorio.unb.br/handle/10482/12625 https://dx.doi.org/10.1371/journal.pone.0037694 |