Hepatitis C virus genotypes in blood donors from the Federal District, Central Brazil
保存先:
| 第一著者: | |
|---|---|
| 出版日付: | 2004 |
| その他の著者: | , , , , , , |
| フォーマット: | Article |
| 言語: | eng |
| ソース: | Repositório Institucional da UnB |
| Download full: | http://repositorio.unb.br/handle/10482/26149 https://dx.doi.org/10.1590/S0074-02762004000800019 |
要約: | The objective of this study was to characterize hepatitis C virus (HCV) genotypes in blood donors from the Federal District, Central Brazil, and to compare HCV screening by serological assays and reverse transcriptase polymerase chain reaction (RT-PCR). Plasma samples from 57 individuals with reactive or indeterminate results in serological anti-HCV screening assays (ELISA or EIA) were tested for HCV RNA by RT-PCR. The results from a confirmatory LIA serological assay were also evaluated. The 5' non-coding region of the HCV genome was amplified from 41 PCR positive samples (71.9%), which were further characterized by nucleotide sequencing analysis. Of these, 60.9% were of HCV genotype 1 and 39.1% of genotype 3. |
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