Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia
Furkejuvvon:
| Váldodahkki: | |
|---|---|
| Almmustuhttinbeaivi: | 2010 |
| Eará dahkkit: | , , , , |
| Materiálatiipa: | Article |
| Giella: | eng |
| Gáldu: | Repositório Institucional da UnB |
| Download full: | http://repositorio.unb.br/handle/10482/27890 https://dx.doi.org/10.1590/S1676-24442010000400004 |
Čoahkkáigeassu: | INTRODUCTION: Serum uric acid has been considered a marker or an element of the clinical and laboratory alterations in the metabolic syndrome. OBJECTIVE: to evaluate the association between levels of serum uric acid (UA) and the following laboratory profile: fasting glucose > 100 mg/dl, triglycerides > 150 mg/dl and high density lipoprotein cholesterol (HDL-C) < 50 mg/dl in women and < 40 mg/dl in men. METHOD: In a cross-sectional survey, blood samples of 4,328 randomized outpatients aged from 20 to 102 years were analyzed. RESULTS: The mean (interquartile range) UA level was higher in men (6.7; 2.4-12.5 mg/dl) and women (5.4; 2.0-12.2 mg/dl) with the laboratorial profile than in those without it (5.9; 0.90-33.8 mg/dl for men and 4.4; 0.8-30.0 mg/dl for women) (p < 0.0001). A significant increase in the prevalence of laboratory profile was observed in men (OR = 2.2 mg/dl; 95% CI: 1.2-3.9 mg/dl) and women (OR = 2.2 mg/dl; 95% CI: 1.4-3.5 mg/dl) with hyperuricemia. CONCLUSION: These results show the association between serum levels of uric acid and metabolic syndrome profile, which corroborates to similar results found in other populations worldwide. |
| _version_ | 1871442397397778432 |
|---|---|
| author | Rosa, Tânia Torres |
| author2 | Moura, Ewandro Luiz Rey Oliveira, Manuela Costa de Boff, Gláucia Junqueira Junior, Luiz Fernando Veiga, Joel Paulo Russomano |
| author2_role | author author author author author |
| author_browse | Boff, Gláucia Junqueira Junior, Luiz Fernando Moura, Ewandro Luiz Rey Oliveira, Manuela Costa de Rosa, Tânia Torres Veiga, Joel Paulo Russomano |
| author_facet | Rosa, Tânia Torres Moura, Ewandro Luiz Rey Oliveira, Manuela Costa de Boff, Gláucia Junqueira Junior, Luiz Fernando Veiga, Joel Paulo Russomano |
| author_role | author |
| bitstream.checksum.fl_str_mv | 1f2c314b42dda0215590296e38f17118 |
| bitstream.checksumAlgorithm.fl_str_mv | MD5 |
| bitstream.url.fl_str_mv | http://repositorio.unb.br/bitstream/10482/27890/1/04.pdf |
| collection | Repositório Institucional da UnB |
| dc.contributor.author.fl_str_mv | Rosa, Tânia Torres Moura, Ewandro Luiz Rey Oliveira, Manuela Costa de Boff, Gláucia Junqueira Junior, Luiz Fernando Veiga, Joel Paulo Russomano |
| dc.date.accessioned.fl_str_mv | 2017-12-07T04:55:18Z |
| dc.date.available.fl_str_mv | 2017-12-07T04:55:18Z |
| dc.date.issued.fl_str_mv | 2010 |
| dc.identifier.citation.fl_str_mv | J. Bras. Patol. Med. Lab.,v.46,n.4,p.283-288,2010 |
| dc.identifier.doi.pt_BR.fl_str_mv | https://dx.doi.org/10.1590/S1676-24442010000400004 |
| dc.identifier.uri.fl_str_mv | http://repositorio.unb.br/handle/10482/27890 |
| dc.language.iso.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia |
| dc.rights.driver.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:Repositório Institucional da UnB instname:Universidade de Brasília (UnB) instacron:UNB |
| dc.subject.keyword.pt_BR.fl_str_mv | Pacientes ambulatoriais Hiperuricemia Hiperglicemia Dislipidemia |
| dc.title.pt_BR.fl_str_mv | Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia A prevalência de hiperuricemia está aumentada em pacientes ambulatoriais com hiperglicemia e dislipidemia |
| dc.type.driver.fl_str_mv | info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv | info:eu-repo/semantics/publishedVersion |
| description | INTRODUCTION: Serum uric acid has been considered a marker or an element of the clinical and laboratory alterations in the metabolic syndrome. OBJECTIVE: to evaluate the association between levels of serum uric acid (UA) and the following laboratory profile: fasting glucose > 100 mg/dl, triglycerides > 150 mg/dl and high density lipoprotein cholesterol (HDL-C) < 50 mg/dl in women and < 40 mg/dl in men. METHOD: In a cross-sectional survey, blood samples of 4,328 randomized outpatients aged from 20 to 102 years were analyzed. RESULTS: The mean (interquartile range) UA level was higher in men (6.7; 2.4-12.5 mg/dl) and women (5.4; 2.0-12.2 mg/dl) with the laboratorial profile than in those without it (5.9; 0.90-33.8 mg/dl for men and 4.4; 0.8-30.0 mg/dl for women) (p < 0.0001). A significant increase in the prevalence of laboratory profile was observed in men (OR = 2.2 mg/dl; 95% CI: 1.2-3.9 mg/dl) and women (OR = 2.2 mg/dl; 95% CI: 1.4-3.5 mg/dl) with hyperuricemia. CONCLUSION: These results show the association between serum levels of uric acid and metabolic syndrome profile, which corroborates to similar results found in other populations worldwide. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | UNB_8e62a964e7fcf41e1bb5d2c21faa4a98 |
| identifier_str_mv | J. Bras. Patol. Med. Lab.,v.46,n.4,p.283-288,2010 |
| instacron_str | UNB |
| institution | UNB |
| instname_str | Universidade de Brasília (UnB) |
| language | eng |
| network_acronym_str | UNB |
| network_name_str | Repositório Institucional da UnB |
| oai_identifier_str | oai:repositorio.unb.br:10482/27890 |
| publishDate | 2010 |
| publishDateSort | 2010 |
| publisher.none.fl_str_mv | Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia |
| reponame_str | Repositório Institucional da UnB |
| repository.mail.fl_str_mv | repositorio@unb.br |
| repository.name.fl_str_mv | Repositório Institucional da UnB - Universidade de Brasília (UnB) |
| repository_id_str | |
| spelling | Rosa, Tânia TorresMoura, Ewandro Luiz ReyOliveira, Manuela Costa deBoff, GláuciaJunqueira Junior, Luiz FernandoVeiga, Joel Paulo Russomano2017-12-07T04:55:18Z2017-12-07T04:55:18Z2010J. Bras. Patol. Med. Lab.,v.46,n.4,p.283-288,2010http://repositorio.unb.br/handle/10482/27890https://dx.doi.org/10.1590/S1676-24442010000400004INTRODUCTION: Serum uric acid has been considered a marker or an element of the clinical and laboratory alterations in the metabolic syndrome. OBJECTIVE: to evaluate the association between levels of serum uric acid (UA) and the following laboratory profile: fasting glucose > 100 mg/dl, triglycerides > 150 mg/dl and high density lipoprotein cholesterol (HDL-C) < 50 mg/dl in women and < 40 mg/dl in men. METHOD: In a cross-sectional survey, blood samples of 4,328 randomized outpatients aged from 20 to 102 years were analyzed. RESULTS: The mean (interquartile range) UA level was higher in men (6.7; 2.4-12.5 mg/dl) and women (5.4; 2.0-12.2 mg/dl) with the laboratorial profile than in those without it (5.9; 0.90-33.8 mg/dl for men and 4.4; 0.8-30.0 mg/dl for women) (p < 0.0001). A significant increase in the prevalence of laboratory profile was observed in men (OR = 2.2 mg/dl; 95% CI: 1.2-3.9 mg/dl) and women (OR = 2.2 mg/dl; 95% CI: 1.4-3.5 mg/dl) with hyperuricemia. CONCLUSION: These results show the association between serum levels of uric acid and metabolic syndrome profile, which corroborates to similar results found in other populations worldwide.INTRODUÇÃO: O ácido úrico sérico tem sido considerado um marcador ou componente das alterações clínicas e laboratoriais da síndrome metabólica. OBJETIVO: Avaliar a associação entre o ácido úrico sérico (AU) e o perfil laboratorial composto de glicemia de jejum > 100 mg/dl, triglicerídeos > 150 mg/dl e colesterol da lipoproteína de alta densidade (HDL-C) < 50 mg/dl nas mulheres e < 40 mg/dl nos homens. MÉTODO: Em estudo de corte transversal, amostras de sangue de 4.328 pacientes ambulatoriais não selecionados com idade variando de 20 a 102 anos foram examinadas. RESULTADOS: A mediana (variação interquartil) do AU foi mais elevada nos homens (6,7; 2,4-12,5 mg/dl) e mulheres (5,4;2-12,2 mg/dl) que apresentaram o perfil laboratorial do que nos que não o apresentaram (5,9; 0,9-33,8 mg/dl para os homens e 4,4; 0,8-30 mg/dl para as mulheres) (p < 0,0001). Observou-se aumento significativo na prevalência do perfil laboratorial nos homens (razão de chance [RC] = 2,2 mg/dl; intervalo de confiança [IC] 95%: 1,2-3,9 mg/dl) e mulheres (RC = 2,2 mg/dl; IC 95%: 1,4-3,5 mg/dl) com hiperuricemia. CONCLUSÃO: Esses resultados mostram a associação dos níveis séricos do acido úrico com o perfil laboratorial da síndrome metabólica nesse grupo não selecionado de indivíduos brasileiros atendidos ambulatorialmente, sendo este um achado semelhante ao observado em outras populações estudadas mundialmente.Em processamentoSociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de CitopatologiaPrevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemiaA prevalência de hiperuricemia está aumentada em pacientes ambulatoriais com hiperglicemia e dislipidemiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlePacientes ambulatoriaisHiperuricemiaHiperglicemiaDislipidemiainfo:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNBORIGINAL04.pdfapplication/pdf173890http://repositorio.unb.br/bitstream/10482/27890/1/04.pdf1f2c314b42dda0215590296e38f17118MD51open access10482/278902024-08-28 13:31:55.351open accessoai:repositorio.unb.br:10482/27890Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2024-08-28T16:31:55Repositório Institucional da UnB - Universidade de Brasília (UnB) |
| spellingShingle | Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia Rosa, Tânia Torres Pacientes ambulatoriais Hiperuricemia Hiperglicemia Dislipidemia |
| status_str | publishedVersion |
| title | Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia |
| title_full | Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia |
| title_fullStr | Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia |
| title_full_unstemmed | Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia |
| title_short | Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia |
| title_sort | Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia |
| topic | Pacientes ambulatoriais Hiperuricemia Hiperglicemia Dislipidemia |
| url | http://repositorio.unb.br/handle/10482/27890 https://dx.doi.org/10.1590/S1676-24442010000400004 |