Piroplasmid infection is not associated with clinicopathological and laboratory abnormalities in cats from midwestern Brazil
Gorde:
| Egile nagusia: | |
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| Argitaratze data: | 2022 |
| Beste egile batzuk: | , , , , , , , , |
| Formatua: | Article |
| Hizkuntza: | eng |
| Baliabidea: | Repositório Institucional da UnB |
| Download full: | http://repositorio.unb.br/handle/10482/52321 https://doi.org/10.1007/s00436-022-07602-8 https://orcid.org/0000-0002-9996-7398 https://orcid.org/0009-0007-9246-3529 https://orcid.org/0000-0002-1106-8962 https://orcid.org/0000-0002-1713-5222 https://orcid.org/0000-0002-2617-2252 https://orcid.org/0000-0002-9112-1718 |
Gaia: | Feline piroplasmids include the genera Babesia spp., Cytauxzoon spp., and Theileria spp. In Brazil, there are few reports regarding these hemoprotozoans; however, clinicopathological and molecular data are scarce. This study aimed to characterize the clinical relevance of these parasites through hematological, biochemical, and molecular approaches. For this purpose, 166 cats from Brasilia, Federal District, Midwestern Brazil, were screened using a quantitative polymerase chain reaction (qPCR) for piroplasmids based on the LSU4 mitochondrial gene, which resulted in an overall prevalence of 36/166 (21.7%). Twelve of 166 samples (7.2%) were positive for C. felis, while 19/166 (11.4%) were positive for Babesia vogeli. No samples tested positive for Theileria spp. Babesia vogeli and Cytauxzoon spp. LSU4 sequences showed identities of 97–100% and 99.3%, respectively, to US isolates. The hematological and biochemical fndings did not difer signifcantly between the cats that tested positive and negative for piroplasmids. Although the lack of abnormalities in clinical and laboratory parameters does not eliminate the possibility that these cats were sick and recovered, it may suggest that the Brazilian strain of Cytauxzoon spp. is not as pathogenic as that from the USA, despite the high molecular identity with North American isolates. |
| _version_ | 1871442329117655040 |
|---|---|
| author | Oliveira, Camila Manoel de |
| author2 | Yang, Sharon Duarte, Matheus Almeida Figueiredo, Daniela Maciel Batista, Liliane Maria do Rosario Marr, Henry Pimentel, Concepta Margaret McManus André, Marcos Rogério Birkenheuer, Adam Joseph Paludo, Giane Regina |
| author2_role | author author author author author author author author author |
| author_browse | André, Marcos Rogério Batista, Liliane Maria do Rosario Birkenheuer, Adam Joseph Duarte, Matheus Almeida Figueiredo, Daniela Maciel Marr, Henry Oliveira, Camila Manoel de Paludo, Giane Regina Pimentel, Concepta Margaret McManus Yang, Sharon |
| author_facet | Oliveira, Camila Manoel de Yang, Sharon Duarte, Matheus Almeida Figueiredo, Daniela Maciel Batista, Liliane Maria do Rosario Marr, Henry Pimentel, Concepta Margaret McManus André, Marcos Rogério Birkenheuer, Adam Joseph Paludo, Giane Regina |
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| bitstream.url.fl_str_mv | http://repositorio.unb.br/bitstream/10482/52321/2/license.txt http://repositorio.unb.br/bitstream/10482/52321/1/p%c3%a1gina%20em%20branco.pdf |
| collection | Repositório Institucional da UnB |
| dc.contributor.affiliation.pt_BR.fl_str_mv | Universidade de Brasília, Faculdade de Agronomia e Medicina Veterinária, Laboratório de Patologia Clínica Veterinária North Carolina State College of Veterinary Medicine, Department of Clinical Sciences Universidade de Brasília, Faculdade de Agronomia e Medicina Veterinária, Laboratório de Patologia Clínica Veterinária Universidade de Brasília, Faculdade de Agronomia e Medicina Veterinária, Laboratório de Patologia Clínica Veterinária Universidade de Brasília, Faculdade de Agronomia e Medicina Veterinária, Laboratório de Patologia Clínica Veterinária North Carolina State College of Veterinary Medicine, Department of Clinical Sciences Universidade de Brasília, Instituto de Ciências Biológicas, Departamento de Ciências Fisiológicas Universidade Estadual Paulista, Faculdade de Ciências Agrárias e Veterinárias Júlio de Mesquita Filho, Departamento de Patologia Veterinária, Laboratório de Imunoparasitologia North Carolina State College of Veterinary Medicine, Department of Clinical Sciences Universidade de Brasília, Faculdade de Agronomia e Medicina Veterinária, Laboratório de Patologia Clínica Veterinária |
| dc.contributor.author.fl_str_mv | Oliveira, Camila Manoel de Yang, Sharon Duarte, Matheus Almeida Figueiredo, Daniela Maciel Batista, Liliane Maria do Rosario Marr, Henry Pimentel, Concepta Margaret McManus André, Marcos Rogério Birkenheuer, Adam Joseph Paludo, Giane Regina |
| dc.date.accessioned.fl_str_mv | 2025-06-06T14:06:35Z |
| dc.date.available.fl_str_mv | 2025-06-06T14:06:35Z |
| dc.date.issued.fl_str_mv | 2022-09 |
| dc.identifier.citation.fl_str_mv | OLIVEIRA, Camila Manoel de. Piroplasmid infection is not associated with clinicopathological and laboratory abnormalities in cats from midwestern Brazil. Parasitology Research, Berlim, v. 121, p. 2561–2570, 2022. DOI: https://doi.org/10.1007/s00436-022-07602-8. Disponível em: https://link.springer.com/article/10.1007/s00436-022-07602-8. Acesso em: 06 jun. 2025. |
| dc.identifier.doi.pt_BR.fl_str_mv | https://doi.org/10.1007/s00436-022-07602-8 |
| dc.identifier.orcid.pt_BR.fl_str_mv | https://orcid.org/0000-0002-9996-7398 https://orcid.org/0009-0007-9246-3529 https://orcid.org/0000-0002-1106-8962 https://orcid.org/0000-0002-1713-5222 https://orcid.org/0000-0002-2617-2252 https://orcid.org/0000-0002-9112-1718 |
| dc.identifier.uri.fl_str_mv | http://repositorio.unb.br/handle/10482/52321 |
| dc.language.iso.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Springer Nature |
| dc.relation.publisherversion.pt_BR.fl_str_mv | https://link.springer.com/article/10.1007/s00436-022-07602-8 |
| dc.rights.driver.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:Repositório Institucional da UnB instname:Universidade de Brasília (UnB) instacron:UNB |
| dc.subject.keyword.pt_BR.fl_str_mv | Piroplasmídeos Bioquímica Hematologia Felinos |
| dc.title.pt_BR.fl_str_mv | Piroplasmid infection is not associated with clinicopathological and laboratory abnormalities in cats from midwestern Brazil |
| dc.type.driver.fl_str_mv | info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv | info:eu-repo/semantics/publishedVersion |
| description | Feline piroplasmids include the genera Babesia spp., Cytauxzoon spp., and Theileria spp. In Brazil, there are few reports regarding these hemoprotozoans; however, clinicopathological and molecular data are scarce. This study aimed to characterize the clinical relevance of these parasites through hematological, biochemical, and molecular approaches. For this purpose, 166 cats from Brasilia, Federal District, Midwestern Brazil, were screened using a quantitative polymerase chain reaction (qPCR) for piroplasmids based on the LSU4 mitochondrial gene, which resulted in an overall prevalence of 36/166 (21.7%). Twelve of 166 samples (7.2%) were positive for C. felis, while 19/166 (11.4%) were positive for Babesia vogeli. No samples tested positive for Theileria spp. Babesia vogeli and Cytauxzoon spp. LSU4 sequences showed identities of 97–100% and 99.3%, respectively, to US isolates. The hematological and biochemical fndings did not difer signifcantly between the cats that tested positive and negative for piroplasmids. Although the lack of abnormalities in clinical and laboratory parameters does not eliminate the possibility that these cats were sick and recovered, it may suggest that the Brazilian strain of Cytauxzoon spp. is not as pathogenic as that from the USA, despite the high molecular identity with North American isolates. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | UNB_5d4bf03e53dca9f1cb212a9779a27ba0 |
| identifier_str_mv | OLIVEIRA, Camila Manoel de. Piroplasmid infection is not associated with clinicopathological and laboratory abnormalities in cats from midwestern Brazil. Parasitology Research, Berlim, v. 121, p. 2561–2570, 2022. DOI: https://doi.org/10.1007/s00436-022-07602-8. Disponível em: https://link.springer.com/article/10.1007/s00436-022-07602-8. Acesso em: 06 jun. 2025. |
| instacron_str | UNB |
| institution | UNB |
| instname_str | Universidade de Brasília (UnB) |
| language | eng |
| network_acronym_str | UNB |
| network_name_str | Repositório Institucional da UnB |
| oai_identifier_str | oai:repositorio.unb.br:10482/52321 |
| publishDate | 2022 |
| publishDateSort | 2022 |
| publisher.none.fl_str_mv | Springer Nature |
| reponame_str | Repositório Institucional da UnB |
| repository.mail.fl_str_mv | repositorio@unb.br |
| repository.name.fl_str_mv | Repositório Institucional da UnB - Universidade de Brasília (UnB) |
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| spelling | Oliveira, Camila Manoel deYang, SharonDuarte, Matheus AlmeidaFigueiredo, Daniela MacielBatista, Liliane Maria do RosarioMarr, HenryPimentel, Concepta Margaret McManusAndré, Marcos RogérioBirkenheuer, Adam JosephPaludo, Giane ReginaUniversidade de Brasília, Faculdade de Agronomia e Medicina Veterinária, Laboratório de Patologia Clínica VeterináriaNorth Carolina State College of Veterinary Medicine, Department of Clinical SciencesUniversidade de Brasília, Faculdade de Agronomia e Medicina Veterinária, Laboratório de Patologia Clínica VeterináriaUniversidade de Brasília, Faculdade de Agronomia e Medicina Veterinária, Laboratório de Patologia Clínica VeterináriaUniversidade de Brasília, Faculdade de Agronomia e Medicina Veterinária, Laboratório de Patologia Clínica VeterináriaNorth Carolina State College of Veterinary Medicine, Department of Clinical SciencesUniversidade de Brasília, Instituto de Ciências Biológicas, Departamento de Ciências FisiológicasUniversidade Estadual Paulista, Faculdade de Ciências Agrárias e Veterinárias Júlio de Mesquita Filho, Departamento de Patologia Veterinária, Laboratório de ImunoparasitologiaNorth Carolina State College of Veterinary Medicine, Department of Clinical SciencesUniversidade de Brasília, Faculdade de Agronomia e Medicina Veterinária, Laboratório de Patologia Clínica Veterinária2025-06-06T14:06:35Z2025-06-06T14:06:35Z2022-09OLIVEIRA, Camila Manoel de. Piroplasmid infection is not associated with clinicopathological and laboratory abnormalities in cats from midwestern Brazil. Parasitology Research, Berlim, v. 121, p. 2561–2570, 2022. DOI: https://doi.org/10.1007/s00436-022-07602-8. Disponível em: https://link.springer.com/article/10.1007/s00436-022-07602-8. Acesso em: 06 jun. 2025.http://repositorio.unb.br/handle/10482/52321https://doi.org/10.1007/s00436-022-07602-8https://orcid.org/0000-0002-9996-7398https://orcid.org/0009-0007-9246-3529https://orcid.org/0000-0002-1106-8962https://orcid.org/0000-0002-1713-5222https://orcid.org/0000-0002-2617-2252https://orcid.org/0000-0002-9112-1718engSpringer Nature© The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022.info:eu-repo/semantics/openAccessPiroplasmid infection is not associated with clinicopathological and laboratory abnormalities in cats from midwestern Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlePiroplasmídeosBioquímicaHematologiaFelinoshttps://link.springer.com/article/10.1007/s00436-022-07602-8Feline piroplasmids include the genera Babesia spp., Cytauxzoon spp., and Theileria spp. In Brazil, there are few reports regarding these hemoprotozoans; however, clinicopathological and molecular data are scarce. This study aimed to characterize the clinical relevance of these parasites through hematological, biochemical, and molecular approaches. For this purpose, 166 cats from Brasilia, Federal District, Midwestern Brazil, were screened using a quantitative polymerase chain reaction (qPCR) for piroplasmids based on the LSU4 mitochondrial gene, which resulted in an overall prevalence of 36/166 (21.7%). Twelve of 166 samples (7.2%) were positive for C. felis, while 19/166 (11.4%) were positive for Babesia vogeli. No samples tested positive for Theileria spp. Babesia vogeli and Cytauxzoon spp. LSU4 sequences showed identities of 97–100% and 99.3%, respectively, to US isolates. The hematological and biochemical fndings did not difer signifcantly between the cats that tested positive and negative for piroplasmids. Although the lack of abnormalities in clinical and laboratory parameters does not eliminate the possibility that these cats were sick and recovered, it may suggest that the Brazilian strain of Cytauxzoon spp. is not as pathogenic as that from the USA, despite the high molecular identity with North American isolates.Faculdade de Agronomia e Medicina Veterinária (FAV)Instituto de Ciências Biológicas (IB)Departamento de Ciências Fisiológicas (IB CFS)Programa de Pós-Graduação em Ciências Animaisreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNBLICENSElicense.txtlicense.txttext/plain102http://repositorio.unb.br/bitstream/10482/52321/2/license.txtaed4704d04bb260d4decd80db311aaa5MD52open accessORIGINALpágina em branco.pdfpágina em branco.pdfapplication/pdf8626http://repositorio.unb.br/bitstream/10482/52321/1/p%c3%a1gina%20em%20branco.pdf226fd709c8349d530a156d2a29a24e5dMD51open access10482/523212025-12-28 13:49:18.461open accessoai:repositorio.unb.br:10482/52321U3VibWlzc8OjbyBlZmV0aXZhZGEgZGUgYWNvcmRvIGNvbSBsaWNlbsOnYSBjb25jZWRpZGEgcGVsbyBhdXRvciBlL291IGRldGVudG9yIGRvcyBkaXJlaXRvcyBhdXRvcmFpcy4KRepositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2025-12-28T16:49:18Repositório Institucional da UnB - Universidade de Brasília (UnB) |
| spellingShingle | Piroplasmid infection is not associated with clinicopathological and laboratory abnormalities in cats from midwestern Brazil Oliveira, Camila Manoel de Piroplasmídeos Bioquímica Hematologia Felinos |
| status_str | publishedVersion |
| title | Piroplasmid infection is not associated with clinicopathological and laboratory abnormalities in cats from midwestern Brazil |
| title_full | Piroplasmid infection is not associated with clinicopathological and laboratory abnormalities in cats from midwestern Brazil |
| title_fullStr | Piroplasmid infection is not associated with clinicopathological and laboratory abnormalities in cats from midwestern Brazil |
| title_full_unstemmed | Piroplasmid infection is not associated with clinicopathological and laboratory abnormalities in cats from midwestern Brazil |
| title_short | Piroplasmid infection is not associated with clinicopathological and laboratory abnormalities in cats from midwestern Brazil |
| title_sort | Piroplasmid infection is not associated with clinicopathological and laboratory abnormalities in cats from midwestern Brazil |
| topic | Piroplasmídeos Bioquímica Hematologia Felinos |
| url | http://repositorio.unb.br/handle/10482/52321 https://doi.org/10.1007/s00436-022-07602-8 https://orcid.org/0000-0002-9996-7398 https://orcid.org/0009-0007-9246-3529 https://orcid.org/0000-0002-1106-8962 https://orcid.org/0000-0002-1713-5222 https://orcid.org/0000-0002-2617-2252 https://orcid.org/0000-0002-9112-1718 |