The control and prevention of COVID-19 transmission in children : a protocol for systematic review and meta-analysis
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| Autor principal: | |
|---|---|
| Publication Date: | 2020 |
| Outros Autores: | , , , , , , , , , , , , , |
| Formato: | Article |
| Idioma: | eng |
| Fonte: | Repositório Institucional da UnB |
| Download full: | https://repositorio.unb.br/handle/10482/40435 http://dx.doi.org/10.1097/MD.0000000000021393 http://orcid.org/0000-0001-5225-385X http://orcid.org/0000-0001-6749-3899 https://orcid.org/0000-0002-7849-2661 http://orcid.org/0000-0002-4596-9590 http://orcid.org/0000-0001-8296-3852 http://orcid.org/0000-0003-3929-2082 https://orcid.org/0000-0002-8246-0603 http://orcid.org/0000-0002-5860-6588 http://orcid.org/0000-0001-7994-4001 http://orcid.org/0000.0003-2134-1667 http://orcid.org/0000-0002-4769-4068 http://orcid.org/0000-0003-1798-2496 http://orcid.org/0000-0003-4968-1364 http://orcid.org/0000-0002-2343-7251 |
Resumo: | Background: The pandemic following the rapid spread of the new SARS-CoV-2 virus has hit all continents and caused thousands of deaths worldwide. Evidence has been published on epidemiological and clinical characteristics of population groups considered at risk; however, information for the other population groups, especially for the child population, is needed. In this context, this protocol describes a systematic review that will aim to identify the evidence on control and prevention of COVID-19 transmission among children and adolescents, as well as to describe the epidemiological profile and clinical and immunological characteristics of COVID-19 in this population. Methods: This protocol will be developed in accordance with PRISMA-P. The searches will be conducted in PubMed, Web of Science, ScienceDirect, EMBASE, and Scopus, seeking clinical trials. Observational studies and case reports with Children and adolescents (≤19 years) infected with SARS-CoV-2 will be included whether they report information on the control of prevention and COVID-19 transmission. Two independent researchers will perform the selection of articles, removal of duplication, and screening by Rayyan QCRI application. Cochrane's RoB 2.0, ROBINS-I, and CASP tools will be used to assess the risk of bias. Meta-analysis, subgroup analyses, and/or descriptive analyses will be carried out based on the data conditions included. Results: A high-quality synthesis of the available evidences on the epidemiological profile, the clinical and immunological characteristics involved in children, and adolescents diagnosed with COVID-19, as well as the participation of this population in the transmission dynamics of SARS-CoV-2 will be provided. Conclusion: This systematic review has an important relevance in the current context because it has a great potential to help the development of new control and prevention strategies in the pediatric population. |
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