Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil
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| Auteur principal: | |
|---|---|
| Date de publication: | 2019 |
| Autres auteurs: | , , |
| Format: | Article |
| Langue: | eng |
| Source: | Repositório Institucional da UnB |
| Download full: | https://repositorio.unb.br/handle/10482/36249 https://doi.org/10.1590/0037-8682-0172-2018 http://orcid.org/0000-0002-2709-1825 |
Résumé: | INTRODUCTION: American tegumentary leishmaniasis (ATL) and leprosy share common areas of prevalence, but reports of coinfection are scarce. METHODS: We report a series of 9 ATL-leprosy cases and discuss the association. An integrative diagram to analyze the clinico-immunological features of coinfection with both diseases. RESULTS: Nine patients with leishmaniasis (5 cutaneous, 3 mucocutaneous, 1 disseminated case) exhibited concurrent infection with distinct clinical forms of leprosy. Our diagram-based analysis evidenced a divergent clinico-immunological spectrum for each disease in 8 out of 9 cases. CONCLUSIONS: The spectrum of ATL-leprosy comorbidity suggests that the host has a specific immune response against each pathogen. |
| _version_ | 1871442285621673984 |
|---|---|
| author | Vernal, Sebastian |
| author2 | Bueno Filho, Roberto Gomes, Ciro Martins Roselino, Ana Maria |
| author2_role | author author author |
| author_browse | Bueno Filho, Roberto Gomes, Ciro Martins Roselino, Ana Maria Vernal, Sebastian |
| author_facet | Vernal, Sebastian Bueno Filho, Roberto Gomes, Ciro Martins Roselino, Ana Maria |
| author_role | author |
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| bitstream.url.fl_str_mv | http://repositorio.unb.br/bitstream/10482/36249/1/ARTIGO_Clinico-immunologicalSectrumAmerican.pdf |
| collection | Repositório Institucional da UnB |
| dc.contributor.author.fl_str_mv | Vernal, Sebastian Bueno Filho, Roberto Gomes, Ciro Martins Roselino, Ana Maria |
| dc.date.accessioned.fl_str_mv | 2020-01-24T10:30:00Z |
| dc.date.available.fl_str_mv | 2020-01-24T10:30:00Z |
| dc.date.issued.fl_str_mv | 2019 |
| dc.identifier.citation.fl_str_mv | VERNAL, Sebastian et al. Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: a case series in Southeastern Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 52, e20180172, 2019. DOI: https://doi.org/10.1590/0037-8682-0172-2018. Disponível em: http://scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100633. Acesso em: 23 jan. 2020. |
| dc.identifier.doi.pt_BR.fl_str_mv | https://doi.org/10.1590/0037-8682-0172-2018 |
| dc.identifier.orcid.none.fl_str_mv | http://orcid.org/0000-0002-2709-1825 |
| dc.identifier.uri.fl_str_mv | https://repositorio.unb.br/handle/10482/36249 |
| dc.language.iso.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Sociedade Brasileira de Medicina Tropical - SBMT |
| dc.rights.driver.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:Repositório Institucional da UnB instname:Universidade de Brasília (UnB) instacron:UNB |
| dc.subject.keyword.pt_BR.fl_str_mv | Leishmaniose Hanseníase Leishmaniose cutânea |
| dc.title.pt_BR.fl_str_mv | Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil |
| dc.type.driver.fl_str_mv | info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv | info:eu-repo/semantics/publishedVersion |
| description | INTRODUCTION: American tegumentary leishmaniasis (ATL) and leprosy share common areas of prevalence, but reports of coinfection are scarce. METHODS: We report a series of 9 ATL-leprosy cases and discuss the association. An integrative diagram to analyze the clinico-immunological features of coinfection with both diseases. RESULTS: Nine patients with leishmaniasis (5 cutaneous, 3 mucocutaneous, 1 disseminated case) exhibited concurrent infection with distinct clinical forms of leprosy. Our diagram-based analysis evidenced a divergent clinico-immunological spectrum for each disease in 8 out of 9 cases. CONCLUSIONS: The spectrum of ATL-leprosy comorbidity suggests that the host has a specific immune response against each pathogen. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | UNB_3d9efae8bfe3e27012a7cf359abb6fa7 |
| identifier_str_mv | VERNAL, Sebastian et al. Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: a case series in Southeastern Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 52, e20180172, 2019. DOI: https://doi.org/10.1590/0037-8682-0172-2018. Disponível em: http://scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100633. Acesso em: 23 jan. 2020. |
| instacron_str | UNB |
| institution | UNB |
| instname_str | Universidade de Brasília (UnB) |
| language | eng |
| network_acronym_str | UNB |
| network_name_str | Repositório Institucional da UnB |
| oai_identifier_str | oai:repositorio.unb.br:10482/36249 |
| publishDate | 2019 |
| publishDateSort | 2019 |
| publisher.none.fl_str_mv | Sociedade Brasileira de Medicina Tropical - SBMT |
| reponame_str | Repositório Institucional da UnB |
| repository.mail.fl_str_mv | repositorio@unb.br |
| repository.name.fl_str_mv | Repositório Institucional da UnB - Universidade de Brasília (UnB) |
| repository_id_str | |
| spelling | Vernal, SebastianBueno Filho, RobertoGomes, Ciro MartinsRoselino, Ana Maria2020-01-24T10:30:00Z2020-01-24T10:30:00Z2019VERNAL, Sebastian et al. Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: a case series in Southeastern Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 52, e20180172, 2019. DOI: https://doi.org/10.1590/0037-8682-0172-2018. Disponível em: http://scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100633. Acesso em: 23 jan. 2020.https://repositorio.unb.br/handle/10482/36249https://doi.org/10.1590/0037-8682-0172-2018http://orcid.org/0000-0002-2709-1825Sociedade Brasileira de Medicina Tropical - SBMTClinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleLeishmanioseHanseníaseLeishmaniose cutâneaINTRODUCTION: American tegumentary leishmaniasis (ATL) and leprosy share common areas of prevalence, but reports of coinfection are scarce. METHODS: We report a series of 9 ATL-leprosy cases and discuss the association. An integrative diagram to analyze the clinico-immunological features of coinfection with both diseases. RESULTS: Nine patients with leishmaniasis (5 cutaneous, 3 mucocutaneous, 1 disseminated case) exhibited concurrent infection with distinct clinical forms of leprosy. Our diagram-based analysis evidenced a divergent clinico-immunological spectrum for each disease in 8 out of 9 cases. CONCLUSIONS: The spectrum of ATL-leprosy comorbidity suggests that the host has a specific immune response against each pathogen.Faculdade de Medicina (FM)info:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNBORIGINALARTIGO_Clinico-immunologicalSectrumAmerican.pdfapplication/pdf1588635http://repositorio.unb.br/bitstream/10482/36249/1/ARTIGO_Clinico-immunologicalSectrumAmerican.pdfb460935d680ebd7f72191658abc21b5bMD51open access10482/362492025-01-14 12:49:46.962open accessoai:repositorio.unb.br:10482/36249Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2025-01-14T15:49:46Repositório Institucional da UnB - Universidade de Brasília (UnB) |
| spellingShingle | Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil Vernal, Sebastian Leishmaniose Hanseníase Leishmaniose cutânea |
| status_str | publishedVersion |
| title | Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil |
| title_full | Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil |
| title_fullStr | Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil |
| title_full_unstemmed | Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil |
| title_short | Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil |
| title_sort | Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil |
| topic | Leishmaniose Hanseníase Leishmaniose cutânea |
| url | https://repositorio.unb.br/handle/10482/36249 https://doi.org/10.1590/0037-8682-0172-2018 http://orcid.org/0000-0002-2709-1825 |