Efficacy of different in-office treatments for dentin hypersensitivity: randomized and parallel clinical trial

• Main Author: Ramos, Fernanda de Souza e Silva [UNESP]
• Publication Date: 2024
• Other Authors: Briso, André Luiz Fraga [UNESP], Albertinazzi, Larissa [UNESP], Marchetti, Vitória Marega [UNESP], Souza, Marina Trevelin, Fagundes, Ticiane Cestari [UNESP]
• Format: Article
• Language: eng
• Source: Repositório Institucional da UNESP
• Download full: http://dx.doi.org/10.1590/0103-6440202405487; https://hdl.handle.net/11449/306149
• topic: Clinical Trial; Dentin Desensitizing Agents; Dentin Sensitivity; Randomized Clinical Trial

The aim of this clinical, prospective, randomized, and parallel study was to evaluate different in-office treatments for dentin hypersensitivity (DH). One hundred ninety-two teeth with non-cavitated root exposures were treated using different desensitizers: fluoride varnish (Duraphat – FLU); bioactive ceramic solution (Biosilicate-BIOS); universal self-etching adhesive (Single Bond Universal – SBU); bioactive photoactivated varnish (PRG filler-SPRG). The degree of DH was analyzed using a visual analog scale (VAS) and computerized visual scale (CoVAS), before treatments and after 7, 15, and 30 days from the first session. Comparisons among desensitizers were performed using the Kruskal-Wallis and Dunn's tests. Friedman test was used to compare between times (p ≤ 0.05). Comparing desensitizers FLU presented a higher value of DH than BIOS using VAS at 7 days, however, no differences were found using CoVAS analysis. Comparing times, BIOS and SBU showed a reduction in DH after 7 days and SBU showed a reduction at 30 days compared to 7 days using VAS. FLU and SPRG groups reduced DH from 15 days to 30 days using VAS. There was a reduction in DH for FLU, BIOS, and SBU after 7 days and for BIOS this reduction also occurred at 30 days when compared to 15 days using CoVAS. SPRG group showed a reduction from 15 to 30 days. All desensitizers tested were able to reduce the initial sensitivity. The bioactive ceramic solution reduced the DH gradually after 30 days using computerized analysis.