Relationship between carotid intima-media thickness, physical activity, sleep quality, metabolic/inflamatory profile, body fatness, smoking and alcohol consumption in young adults

• Main Author: Maillane-vanegas, Santiago
• Publication Date: 2017
• Other Authors: Turi-lynch, Bruna Camilo, Lira, Fabio Santos De, Codogno, Jamile Sanches, Fernandes, Rômulo Araújo, Lima, Manoel Carlos Spiguel De, Machado-rodrigues, Aristides, Kemper, Han C. G.
• Format: Article
• Language: eng
• Source: Repositório Institucional da UNESP
• Download full: http://dx.doi.org/10.1590/s1980-6574201700030020; http://hdl.handle.net/11449/157925
• topic: Aatherosclerosis; insulin resistance; lipid profile; diabetes mellitus

AbstractAIM The aim of this longitudinal study was to analyze the relationship between sleep disorder and intima-media thickness.METHOD Baseline measurements included carotid intima-media thickness, assessed by an ultrasound device; questionnaires about sleep and other behavioral variables; physical activity was measured by pedometer; body fatness was estimated by Dual-Energy X-ray Absorptiometry; fasting glucose, lipid profile and C-reactive protein were collected.RESULTS The occurrence rate of sleep-related disorders was 47% (95%CI= 37.2%-56.7%). Carotid intima-media thickness was related to symptoms of insomnia (r= 0.328 [0.141 to 0.493]) and, after adjustments for potential confounders, the relationship between carotid intima-media thickness and insomnia remained statistically significant (β= 0.121 [95%CI= 0.017; 0.225]).CONCLUSIONS In young adults, sleep disorder was significantly related to premature increase in carotid intima-media thickness.